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Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups.
The virological features and clinical findings associated with the new human metapneumovirus (HMPV) were examined retrospectively in Canadian patients hospitalized for various respiratory conditions since 1993 and suggest that HMPV can be associated with severe lower-respiratory-tract infections in very young children, the elderly, and immunocompromised patients.
Human Metapneumovirus Infections in Hospitalized Children
HMPV is an important cause of illness in young children with a similar, although less severe, clinical presentation to that of HRSV.
Impact of extreme temperatures on parasitoids in a climate change perspective.
A careful analysis on how host-parasitoid systems react to changes in temperature is needed so that researchers may predict and manage the consequences of global change at the ecosystem level.
Quantitation of Cytomegalovirus: Methodologic Aspects and Clinical Applications
SUMMARY Cytomegalovirus (CMV) is an important pathogen in transplant recipients and human immunodeficiency virus (HIV)-infected individuals. Major progress has been made in developing quantitative…
Resistance of Herpes Simplex Viruses to Nucleoside Analogues: Mechanisms, Prevalence, and Management
The gold standard phenotypic method for evaluating the susceptibility of HSV isolates to antiviral drugs is the plaque reduction assay and there is a need to develop new antiherpetic compounds with different mechanisms of action.
Human Cytomegalovirus Resistance to Antiviral Drugs
Active HCMV infections have been associated with indirect effects, such as dysfunction or rejection of the transplanted organ, an increased risk for bacterial or fungal opportunistic infections, and accelerated atherosclerosis in heart transplant recipients (109), with the highest incidence seen in D+/R− patients.
Insect parasitoids cold storage: A comprehensive review of factors of variability and consequences
Resistance of herpesviruses to antiviral drugs: clinical impacts and molecular mechanisms.
Characterization of Human Metapneumoviruses Isolated from Patients in North America
Sequence studies of the nucleocapsid, fusion, and polymerase genes identified 2 main lineages of HMPV and cocirculation of both lineages during the same year.
Association between the 2008–09 Seasonal Influenza Vaccine and Pandemic H1N1 Illness during Spring–Summer 2009: Four Observational Studies from Canada
Prior receipt of 2008-09 TIV was associated with increased risk of medically attended pH1N1 illness during the spring-summer 2009 in Canada and possible biological mechanisms and immunoepidemiologic implications are considered.