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Ribonucleoprotein, U4-U6 Small Nuclear

Known as: U4 U6 Small Nuclear Ribonucleoproteins, U4-U6 Small Nuclear Ribonucleoproteins, U4-U6 snRNP 
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U4-U6 snRNP along with the U5 snRNP preassemble into a… 
National Institutes of Health

Related topics

Related topics

18 relations
In BloodProcess of secretionagonistsantagonists & inhibitors

Narrower (9)

LSM4 protein, S cerevisiaePRP6 protein, S cerevisiaePRPF3 protein, humanPRPF4B protein, human

Broader (1)

U4/U6 snRNP

Papers overview

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Review
2007
Review
2007
The structure and function of small nucleolar ribonucleoproteins
Eukaryotes and archaea use two sets of specialized ribonucleoproteins (RNPs) to carry out sequence-specific methylation and… 
Highly Cited
2006
Highly Cited
2006
Enhancement of U4/U6 small nuclear ribonucleoprotein particle association in Cajal bodies predicted by mathematical modeling.
Spliceosomal small nuclear ribonucleoprotein particles (snRNPs) undergo specific assembly steps in Cajal bodies (CBs… 
Highly Cited
2003
Highly Cited
2003
Targeting of U4/U6 small nuclear RNP assembly factor SART3/p110 to Cajal bodies
The spliceosomal small nuclear RNAs (snRNAs) are distributed throughout the nucleoplasm and concentrated in nuclear inclusions… 
Highly Cited
2003
Highly Cited
2003
U1 snRNP-Dependent Function of TIAR in the Regulation of Alternative RNA Processing of the Human Calcitonin/CGRP Pre-mRNA
ABSTRACT Alternative RNA processing of human calcitonin/CGRP pre-mRNA is regulated by an intronic enhancer element. Previous… 
Highly Cited
2000
Highly Cited
2000
A Common Core RNP Structure Shared between the Small Nucleoar Box C/D RNPs and the Spliceosomal U4 snRNP
Highly Cited
1999
Highly Cited
1999
A Novel Genetic Screen for snRNP Assembly Factors in Yeast Identifies a Conserved Protein, Sad1p, Also Required for Pre-mRNA Splicing
ABSTRACT The assembly pathway of spliceosomal snRNPs in yeast is poorly understood. We devised a screen to identify mutations… 
Highly Cited
1992
Highly Cited
1992
Reconstituted mammalian U4/U6 snRNP complements splicing: a mutational analysis.
We have developed an in vitro complementation assay to analyse the functions of U6 small nuclear RNA (snRNA) in splicing and in… 
Highly Cited
1989
Highly Cited
1989
Antisense probing of the human U4 U6…
Highly Cited
1989
Highly Cited
1989
In vitro assembly of yeast U6 snRNP: a functional assay.
U6 small nuclear RNA (snRNA) is the most highly conserved spliceosomal RNA, and it has been postulated to have a fundamental role… 
Highly Cited
1989
Highly Cited
1989
An abundant U6 snRNP found in germ cells and embryos of Xenopus laevis.
The particle state of U snRNPs was analyzed in oocytes, eggs, embryos and testes from Xenopus laevis. In each case both the… 
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