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Rho Guanine Nucleotide Exchange Factors

Known as: Rho Guanine Nucleotide Exchange Factors [Chemical/Ingredient] 
Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in… 
National Institutes of Health

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ARHGEF10 protein, humanARHGEF12 protein, humanARHGEF4 protein, humanARHGEF5 protein, human
ARHGEF28 geneIn BloodProcess of secretionRho guanine nucleotide exchange factor activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Screening for Rho GTPase Modulators in Actin-Dependent Processes Exemplified by Phagocytosis.
Rho GTPases, a family of molecular switches, are essential for the assembly and rearrangement of the cellular actin network… 
2017
2017
JCB_201704145 3959..3970
Cells undergo continuous stress, both mechanical and chemical, which can lead to ruptures in the cell membrane and damage to the… 
2016
2016
Potent and Selective Peptide-based Inhibition of the G Protein Gαq*
In contrast to G protein-coupled receptors, for which chemical and peptidic inhibitors have been extensively explored, few… 
2015
2015
Catching Functional Modes and Structural Communication in Dbl Family Rho Guanine Nucleotide Exchange Factors
Computational approaches such as Principal Component Analysis (PCA) and Elastic Network Model-Normal Mode Analysis (ENM-NMA) are… 
2013
2013
Cooperation between Rho-GEF Gef2 and its binding partner Nod1 in the regulation of fission yeast cytokinesis
Previous results showed that putative Rho-GEF Gef2 regulates division-site positioning during early cytokinesis in fission yeast… 
2011
2011
Plasma Membrane Association of p63 Rho Guanine Nucleotide Exchange Factor (p63RhoGEF) Is Mediated by Palmitoylation and Is Required for Basal Activity in Cells*
Activation of G protein-coupled receptors at the cell surface leads to the activation or inhibition of intracellular effector… 
2011
2011
Activity in Cells Palmitoylation and Is Required for Basal ( p 63 RhoGEF ) Is Mediated by Guanine Nucleotide Exchange Factor Plasma Membrane Association of p 63 Rho Signal Transduction :
2011
2011
Modeling hyperactivity: of mice and men
Although attention deficit hyperactivity disorder (ADHD) is a highly heritable and common psychiatric disorder, few… 
2007
2007
EhGEF3, a novel Dbl family member, regulates EhRacA activation during chemotaxis and capping in Entamoeba histolytica.
Rho GTPases are critical elements involved in the regulation of signal transduction cascades from extracellular stimuli to… 
2004
2004
Modular architecture and novel protein-protein interactions regulating the RGS-containing Rho guanine nucleotide exchange factors.
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