Replicon

Known as: Replicons, Unit, Replication, genetic replication 
Any DNA sequence capable of independent replication or a molecule that possesses a REPLICATION ORIGIN and which is therefore potentially capable of… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
OBJECTIVES IncF plasmids are frequently encountered in clinical enterobacterial strains associated with the dissemination of… (More)
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Highly Cited
2007
Highly Cited
2007
Despite the critical role of plasmids in horizontal gene transfer, few studies have characterized plasmid relatedness among… (More)
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Highly Cited
2005
Highly Cited
2005
Hepatitis C virus (HCV) infection causes chronic liver diseases and is a global public health problem. Detailed analyses of HCV… (More)
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Highly Cited
2001
Highly Cited
2001
Chronic hepatitis C virus (HCV) infections can be cured only in a fraction of patients treated with alpha interferon (IFN-alpha… (More)
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Highly Cited
1999
Highly Cited
1999
An estimated 170 million persons worldwide are infected with hepatitis C virus (HCV), a major cause of chronic liver disease… (More)
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Highly Cited
1999
Highly Cited
1999
Poliovirus RNA genomes that contained deletions in the capsid-coding regions were synthesized in monkey kidney cells that… (More)
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Highly Cited
1998
Highly Cited
1998
In proliferating cells, DNA synthesis must be performed with extreme precision. We show that groups of replicons, labeled… (More)
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Highly Cited
1991
Highly Cited
1991
We have developed a novel DNA expression system, based on the Semliki Forest virus (SFV) replicon, which combines a wide choice… (More)
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Highly Cited
1989
Highly Cited
1989
A series of yeast shuttle vectors and host strains has been created to allow more efficient manipulation of DNA in Saccharomyces… (More)
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Highly Cited
1983
Highly Cited
1983
We have developed a new vector strategy for the insertion of foreign genes into the genomes of gram negative bacteria not closely… (More)
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