Renal Agents

Known as: Agents, Renal, drugs renal, renal drug 
Drugs used for their effects on the kidneys' regulation of body fluid composition and volume. The most commonly used are the diuretics. Also included… (More)
National Institutes of Health

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Highly Cited
2011
Highly Cited
2011
Drug-drug interactions (DDIs) are major causes of serious adverse drug reactions. Most DDIs have a pharmacokinetic basis in which… (More)
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2011
2011
Chronic renal failure (CRF) leads to decreased drug renal clearance due to a reduction in the glomerular filtration rate. However… (More)
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2008
2008
Gabapentin is an anticonvulsant that is widely prescribed for epilepsy and other neuropathic disorders. The pharmacokinetics… (More)
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2008
2008
BACKGROUND The National Kidney Foundation's practice guidelines for chronic kidney disease recommend using the Modification of… (More)
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2007
2007
BACKGROUND Active renal secretion of tenofovir (TFV) across proximal tubules occurs via uptake by human organic anion… (More)
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2007
2007
BACKGROUND Aliskiren is an orally active direct renin inhibitor approved for the treatment of hypertension. This study assessed… (More)
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Highly Cited
2006
Highly Cited
2006
Tenofovir (TFV) undergoes renal elimination by a combination of glomerular filtration and active tubular secretion. While… (More)
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2004
2004
Purpose. Because the urinary excretion of drugs is often decreased in renal diseases, dosage regimens are adjusted to avoid… (More)
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Highly Cited
1989
Highly Cited
1989
The pathogenesis of aminoglycoside nephrotoxicity is intimately related to the extent of drug accumulated in the renal cortex. In… (More)
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Highly Cited
1988
Highly Cited
1988
Existing methods for predicting creatinine clearance provide accurate estimates for normal-weight patients but not for patients… (More)
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