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Recombinant Immune Globulin

Known as: Therapeutic Immune Globulin, Gamma Globulin, IgIV 
A preparation of plasma proteins derived from the pooled plasma of adult donors. Largely comprised of IgG antibodies, therapeutic immune globulin… Expand
National Institutes of Health

Related topics

Related topics

6 relations
Gamma globulinGamma globulin measurementImmunoglobulins, IntravenousNCIt Antineoplastic Agent Terminology
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Normal Horse Serum

Papers overview

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Highly Cited
2015
Highly Cited
2015
Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles—Part 1: Separation-based methods
Immunoglobulin G (IgG) crystallizable fragment (Fc) glycosylation is crucial for antibody effector functions, such as antibody… Expand
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Highly Cited
2015
Highly Cited
2015
Comparison of methods for the analysis of therapeutic immunoglobulin G Fc-glycosylation profiles—Part 2: Mass spectrometric methods
To monitor the Fc glycosylation of therapeutic immunoglobulin G in bioprocess development, product characterization and release… Expand
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Review
2013
Review
2013
Adverse effects of human immunoglobulin therapy.
Human immunoglobulin (IG) is used for IgG replacement therapy in primary and secondary immunodeficiency, for prevention and… Expand
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Review
2008
Review
2008
Immunoprophylaxis of RSV infection: advancing from RSV-IGIV to palivizumab and motavizumab.
Antibodies mediate humoral immune responses and play key roles in the defense of viral infection by the recognition… Expand
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Highly Cited
2007
Highly Cited
2007
Physiologically-based pharmacokinetic (PBPK) model to predict IgG tissue kinetics in wild-type and FcRn-knockout mice
Although it is known that FcRn, the neonatal Fc-receptor, functions to protect immune gamma globulin (IgG) from elimination, the… Expand
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Highly Cited
2007
Highly Cited
2007
Characterization of protein aggregation: the case of a therapeutic immunoglobulin.
In this paper, a therapeutic immunoglobulin (Antibody A) has been characterized in two solutions: (1) 0.1% acetic acid containing… Expand
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Review
2006
Review
2006
Intravenous immunoglobulin in autoimmune disorders: an insight into the immunoregulatory mechanisms.
Intravenous immunoglobulin (IGIV) has increasingly been used for the treatment of autoimmune and systemic inflammatory diseases… Expand
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Highly Cited
2004
Highly Cited
2004
Characterization of Antibodies to Capsular Polysaccharide Antigens of Haemophilus influenzae Type b and Streptococcus pneumoniae in Human Immune Globulin Intravenous Preparations
ABSTRACT The most common infections in primary immune deficiency disease (PIDD) patients involve encapsulated bacteria, mainly… Expand
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Review
2003
Review
2003
Risks associated with the use of intravenous immunoglobulin.
Although US immune globulin intravenous (human) (IGIV) products have been regarded as safe, it is important to recognize that… Expand
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Highly Cited
1988
Highly Cited
1988
The half-lives of IgG subclasses and specific antibodies in patients with primary immunodeficiency who are receiving intravenously administered immunoglobulin.
With the increased use of immunoglobulin for intravenous use (IGIV) as replacement therapy for patients with primary… Expand
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