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Receptors, Purinergic P2Y2

Known as: Puringergic Receptor P2Y, G-Protein Coupled, 2, Receptors, P2Y2, Receptors, P2U 
A subclass of purinergic P2Y receptors that have a preference for ATP and UTP. The activated P2Y2 receptor acts through a G-PROTEIN-coupled… 
National Institutes of Health

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In BloodP2RY2 geneaspects of radiation effectsphysiological aspects

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P2RY2 protein, human

Papers overview

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2018
2018
Coupling of P2Y receptors to Ca2+ mobilization in mesenchymal stromal cells from the human adipose tissue.
2011
2011
Activation of P2Y1 and P2Y2 receptors induces chloride secretion via calcium-activated chloride channels in kidney inner medullary collecting duct cells.
Dysregulation of urinary sodium chloride (NaCl) excretion can result in extracellular fluid (ECF) volume expansion and… 
2010
2010
Immunogold electron microscopic evidence of in situ formation of homo- and heteromeric purinergic adenosine A1 and P2Y2 receptors in rat brain
BackgroundPurines such as adenosine and ATP are now generally recognized as the regulators of many physiological functions, such… 
2006
2006
Diadenosine and diuridine poly(borano)phosphate analogues: synthesis, chemical and enzymatic stability, and activity at P2Y1 and P2Y2 receptors.
Dinucleoside polyphosphates, NpnN', exert their physiological effects via P2 receptors. They are attractive drug targets as they… 
2004
2004
Subtype specific internalization of P2Y1 and P2Y2 receptors induced by novel adenosine 5′‐O‐(1‐boranotriphosphate) derivatives
P2Y‐nucleotide receptors represent important targets for drug development. The lack of stable and receptor specific agonists… 
Highly Cited
1999
Highly Cited
1999
Functional heterogeneity of endothelial P2 purinoceptors in the cerebrovascular tree of the rat.
The effects of stimulating P2Y1 or P2Y2 purinoceptors on the endothelium of isolated middle cerebral arteries (MCAs), third-order… 
1998
1998
P2Y and P2U receptors differentially release intracellular Ca2+ via the phospholipase C/inositol 1,4,5-triphosphate pathway in astrocytes from the dorsal spinal cord
1998
1998
Nucleotide‐evoked calcium signals and anion secretion in equine cultured epithelia that express apical P2Y2 receptors and pyrimidine nucleotide receptors
Experiments with a spontaneously transformed equine epithelial cell line showed that certain nucleotides increased intracellular… 
1998
1998
Culture substrate‐specific expression of P2Y2 receptors in distal lung epithelial cells isolated from foetal rats
ATP and UTP did not evoke [Ca2+]i signals in rat foetal lung epithelial cells grown on glass but elicited clear responses in… 
1998
1998
Functional expression of P2U receptors in rat spermatogenic cells: dual modulation of a Ca(2+)-activated K+ channel.
Previous study has demonstrated functional expression of a sperm Ca(2+)-activated K+ channel in Xenopus oocytes injected with… 
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