P2RY2 protein, human

Known as: P2Y Purinoceptor 2, Purinergic Receptor P2Y2, P2U Purinoceptor 1 
P2Y purinoceptor 2 (377 aa, ~42 kDa) is encoded by the human P2RY2 gene. This protein plays a role in ligand-dependent activation of second messenger… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Virtually, all tumor cells as well as all immune cells express plasma membrane receptors for extracellular nucleosides (adenosine… (More)
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Highly Cited
2005
Highly Cited
2005
P2X7 is a bifunctional receptor (P2X7R) for extracellular ATP that, depending on the level of activation, forms a cation… (More)
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Highly Cited
2003
Highly Cited
2003
Extracellular nucleotides, including ATP, have been demonstrated to transmit important physiological signals in the brain through… (More)
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Highly Cited
2003
Highly Cited
2003
Microglial cells are the pathologic sensors in the brain. ATP released from damaged cells is a candidate for signalling neural… (More)
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Highly Cited
1998
Highly Cited
1998
ATP-gated cation channels (P2X receptors) exist on the soma of proprioceptive neurons in the trigeminal mesencephalic nucleus… (More)
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Highly Cited
1997
Highly Cited
1997
A cDNA was isolated from a human monocyte library that encodes the P2X7 receptor; the predicted protein is 80% identical to the… (More)
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Highly Cited
1997
Highly Cited
1997
Accumulation of extracellular and intracellular adenosine (Ado) under hypoxic conditions or in the absence of adenosine deaminase… (More)
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Highly Cited
1994
Highly Cited
1994
THE adenosine-5′-triphosphate (ATP) molecule is an extracellular messenger in neural and non-neural tissues, where it activates… (More)
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Highly Cited
1994
Highly Cited
1994
The Cl- secretory pathway that is defective in cystic fibrosis (CF) can be bypassed by an alternative pathway for Cl- transport… (More)
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Highly Cited
1993
Highly Cited
1993
A cDNA encoding a novel member of the G-protein-coupled receptor (GCR) superfamily, an ATP receptor, has been isolated from an… (More)
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