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Receptors, Purinergic P2Y12

Known as: P2Y12 Receptors, Purinergic, P2Y12 Purinoceptors, P2T, Purinoceptor 
A subclass of purinergic P2Y receptors that have a preference for ADP binding and are coupled to GTP-BINDING PROTEIN ALPHA SUBUNIT, GI. The P2Y12… 
National Institutes of Health

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4 relations
In BloodP2RY12 geneaspects of radiation effectsphysiological aspects

Papers overview

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2014
2014
A platelet P-selectin test predicts adverse cardiovascular events in patients with acute coronary syndromes treated with aspirin and clopidogrel
Abstract There is wide variation in response to antiplatelet therapy and high on-treatment platelet reactivity is associated with… 
2013
2013
Effect on Platelet Reactivity From a Prasugrel Loading Dose After a Clopidogrel Loading Dose Compared With a Prasugrel Loading Dose Alone: Transferring From Clopidogrel Loading Dose to Prasugrel…
Background—Adding a prasugrel loading dose (LD) to a clopidogrel LD could be desirable because clopidogrel may fail to provide… 
2007
2007
Evidence that ATP or a related purine is an excitatory neurotransmitter in the longitudinal muscle of mouse distal colon
This study analysed the contribution of the purinergic system to enteric neurotransmission in the longitudinal muscle of mouse… 
2004
2004
Involvement of Sodium in Early Phosphatidylserine Exposure and Phospholipid Scrambling Induced by P2X7 Purinoceptor Activation in Thymocytes*
Extracellular ATP (ATPec), a possible effector in thymocyte selection, induces thymocyte death via purinoceptor activation. We… 
Highly Cited
2002
Highly Cited
2002
Dynamic Pattern of Reg-2 Expression in Rat Sensory Neurons after Peripheral Nerve Injury
The 16 kDa pancreatitis-associated protein Reg-2 has recently been shown to facilitate the regeneration of motor and sensory… 
2001
2001
Activity of adenosine diphosphates and triphosphates on a P2YT‐type receptor in brain capillary endothelial cells
A P2Y (nucleotide) receptor activity in a clonal population (B10) of rat brain capillary endothelial cells is coupled to… 
Highly Cited
1999
Highly Cited
1999
P2 purinoceptor-mediated dilations in the rat middle cerebral artery after ischemia-reperfusion.
Endothelial-mediated dilations to selective P2Y1 and P2Y2 purinoceptor agonists [2-methylthioadenosine triphosphate (2MeS-ATP… 
1998
1998
P 2 purinoceptor-mediated dilations in the rat middle cerebral artery after ischemia-reperfusion
Marrelli, Sean P., Andrei Khorovets, T. David Johnson, William F. Childres, and Robert M. Bryan, Jr. P2 purinoceptor-mediated… 
1997
1997
An ATP‐gated cation channel with some P2Z‐like characteristics in gastric smooth muscle cells of toad.
1. Whole‐cell and single‐channel currents elicited by extracellular ATP were studied in freshly dissociated smooth muscle cells… 
Highly Cited
1997
Highly Cited
1997
Confocal imaging analysis of ATP-induced Ca2+ response in individual endothelial cells of the artery in situ.
The mechanisms for mobilization of intracellular free Ca2+ have been studied in various types of isolated and cultured cells, but… 
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