P2RY12 gene

Known as: PURINORECEPTOR P2Y12, P2RY12, HORK3 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2017
051020012017

Papers overview

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2016
2016
Currently approved platelet adenosine diphosphate (ADP) receptor antagonists target only the platelet P2Y12 receptor. Moreover… (More)
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2015
2015
Tumor cells use activated platelets to promote their proliferation and metastatic potential. Because platelet activation is… (More)
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2014
2014
AIMS Platelets have a fundamental role in atherothrombosis, but their role in early atherogenesis is unclear. The P2Y12 receptor… (More)
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2013
2013
OBJECTIVES This study sought to assess the usefulness of clopidogrel-pathway genotyping and on-treatment platelet reactivity (OTR… (More)
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2010
2010
The use of antiplatelet agents, specifically the thienopyridines, has become a standard of care in the approach to the patient… (More)
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2007
2007
Purinergic receptors are a class of cell surface receptors for purines that prefer ATP or ADP over adenosine. The surface… (More)
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2004
2004
Adenosine diphosphate (ADP), an important platelet agonist, acts through 2 Gprotein–coupled receptors (GPCRs), P2Y1 and P2Y12… (More)
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Highly Cited
2001
Highly Cited
2001
ADP plays a critical role in modulating thrombosis and hemostasis. ADP initiates platelet aggregation by simultaneous activation… (More)
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Highly Cited
2001
Highly Cited
2001
P2Y receptors are a class of G protein-coupled receptors activated primarily by ATP, UTP, and UDP. Five mammalian P2Y receptors… (More)
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2001
2001
Platelet activation plays an essential role in thrombosis. ADP-induced platelet aggregation is mediated by two distinct G protein… (More)
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