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P2RY12 gene

Known as: PURINORECEPTOR P2Y12, P2RY12, HORK3 
 
National Institutes of Health

Papers overview

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2017
2017
The role of resident microglial cells in the pathogenesis and progression of glial tumors is still obscure mainly due to a lack… Expand
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2016
2016
Abstract Cangrelor is a rapid-acting, direct-binding, and reversible P2Y12 antagonist which has been studied for use during… Expand
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2015
2015
C-type lectin like receptor 2 (CLEC-2) has been reported to activate platelets through a lipid raft-dependent manner. Secreted… Expand
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Highly Cited
2012
Highly Cited
2012
The adenosine diphosphate (ADP) receptor P2RY12 (purinergic receptor P2Y, G protein coupled, 12) plays a critical role in… Expand
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2010
2010
The use of antiplatelet agents, specifically the thienopyridines, has become a standard of care in the approach to the patient… Expand
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2005
2005
CS-747 (Prasugrel, LY640315) is a thienopyridine antiplatelet prodrug that is metabolized to the thiol-containing active… Expand
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Highly Cited
2001
Highly Cited
2001
ADP plays a critical role in modulating thrombosis and hemostasis. ADP initiates platelet aggregation by simultaneous activation… Expand
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Review
2001
Review
2001
The action of extracellular nucleotides, specifically the ability of adenine nucleotides to induce coronary vasodilation and… Expand
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Highly Cited
2001
Highly Cited
2001
P2Y receptors are a class of G protein-coupled receptors activated primarily by ATP, UTP, and UDP. Five mammalian P2Y receptors… Expand
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Highly Cited
2001
Highly Cited
2001
Platelet activation plays an essential role in thrombosis. ADP-induced platelet aggregation is mediated by two distinct G protein… Expand
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