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Receptors, CCR7

Known as: CC Chemokine Receptor CCR7, Epstein-Barr Virus-Induced G-Protein Coupled Receptor 1, C-C Chemokine Receptor Type 7 
C-C chemokine receptor type 7 (378 aa, ~43 kDa) is encoded by the human CCR7 gene. This protein plays a role in memory T-cell migration and dendritic… 
National Institutes of Health

Related topics

Related topics

25 relations
CCR7 geneChemokine Receptor GeneCytokine Receptor GeneCytokine Signaling Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Dendritic cells derived exosomes migration to spleen and induction of inflammation are regulated by CCR7
Mature dendritic cells (DCs) home to secondary lymphoid organs through CC chemokine receptor 7 (CCR7). Exosomes derived from DCs… 
Highly Cited
2009
Highly Cited
2009
Hypoxia-induced CCR7 expression via HIF-1α and HIF-2α correlates with migration and invasion in lung cancer cells
Hypoxia, a common phenomenon in human solid tumors, is associated with invasion and metastasis in various tumors. Hypoxia… 
Highly Cited
2009
Highly Cited
2009
Uptake of CCR7 and acquisition of migratory properties by human KIR+ NK cells interacting with monocyte-derived DC or EBV cell lines: regulation by KIR/HLA-class I interaction.
C-C chemokine receptor type 7 (CCR7) is a chemokine receptor playing a pivotal role in the induction of human natural killer (NK… 
Highly Cited
2006
Highly Cited
2006
Human Melanoma Metastases Express Functional CXCR4
Purpose: The chemokine receptor CXCR4 was identified as an independent predictor of poor prognosis in primary melanoma. The aim… 
2006
2006
Oral and oropharyngeal squamous cell carcinomas expressing CCR7 have poor prognoses.
Highly Cited
2006
Highly Cited
2006
Acute effects of hemodialysis on cytokine transcription profiles: evidence for C-reactive protein-dependency of mediator induction.
Chronic microinflammation increases cardiovascular morbidity in chronic hemodialysis (HD) patients. Previously published studies… 
2004
2004
Determinants of high-affinity binding and receptor activation in the N-terminus of CCL-19 (MIP-3 beta).
CC chemokine receptor 7 (CCR-7) is expressed on mature dendritic cells and T-cells. Its ligands, CCL-19 (MIP-3beta) and CCL-21… 
Highly Cited
2003
Highly Cited
2003
Association of CC chemokine receptor 7 with lymph node metastasis of esophageal squamous cell carcinoma.
PURPOSE CC chemokine receptor 7 (CCR7) plays a critical role in the migration of activated dendritic cells to regional lymph… 
2001
2001
A DAP 12-mediated Pathway Regulates Expression of CC Chemokine Receptor 7 and Maturation of Human Dendritic Cells
Gene targeting of the adaptor molecule DAP12 in mice caused abnormal distribution and impaired antigen presentation capacity of… 
Highly Cited
1998
Highly Cited
1998
Secondary Lymphoid-tissue Chemokine Is a Functional Ligand for the CC Chemokine Receptor CCR7*
Secondary Lymphoid-tissueChemokine (SLC) is a recently identified CC chemokine that is constitutively expressed in various… 
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