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Receptor Tyrosine-Protein Kinase ErbB-4, human

Known as: Receptor Tyrosine-Protein Kinase ErbB-4, erbB4, c-erbB-4 
Receptor tyrosine-protein kinase erbB-4 (1308 aa, ~147 kDa) is encoded by the human ERBB4 gene. This protein is involved in multicellular organismal… 
National Institutes of Health

Related topics

Related topics

31 relations
Biologic DevelopmentBrainCell Differentiation processCell Growth Regulation

Broader (1)

ERBB4 Receptor Protein Tyrosine Kinase

Papers overview

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Highly Cited
2014
Highly Cited
2014
MicroRNA-193a-3p and -5p suppress the metastasis of human non-small-cell lung cancer by downregulating the ERBB4/PIK3R3/mTOR/S6K2 signaling pathway
The metastatic cascade is a complex and multistep process with many potential barriers. Recent evidence has shown that microRNAs… 
Highly Cited
2014
Highly Cited
2014
Classic Selective Sweeps Revealed by Massive Sequencing in Cattle
Human driven selection during domestication and subsequent breed formation has likely left detectable signatures within the… 
Highly Cited
2011
Highly Cited
2011
Neuregulin 1 Promotes Excitatory Synapse Development and Function in GABAergic Interneurons
Neuregulin 1 (NRG1) and its receptor ErbB4 are both susceptibility genes of schizophrenia. However, little is known about the… 
Highly Cited
2007
Highly Cited
2007
Inhibition of the EGF Receptor by Binding to an Activating Kinase Domain Interface
Members of the epidermal growth factor receptor family (EGFR/ERBB1, ERBB2/HER2, ERBB3/HER3 and ERBB4/HER4) are key targets for… 
Highly Cited
2004
Highly Cited
2004
Receptor tyrosine kinase ErbB4 modulates neuroblast migration and placement in the adult forebrain
Neural progenitor proliferation, differentiation and migration are continually active in the rostral migratory stream of the… 
Review
2003
Review
2003
Stress and Radiation-Induced Activation of Multiple Intracellular Signaling Pathways1
Abstract Dent, P., Yacoub, A., Contessa, J., Caron, R., Amorino, G., Valerie, K., Hagan, M. P., Grant, S. and Schmidt-Ullrich, R… 
Highly Cited
2003
Highly Cited
2003
Defective valvulogenesis in HB‐EGF and TACE‐null mice is associated with aberrant BMP signaling
Heparin‐binding epidermal growth factor (HB‐EGF) and betacellulin (BTC) are activating ligands for EGF receptor (EGFR/ErbB1) and… 
Highly Cited
2003
Highly Cited
2003
Neural development of the neuregulin receptor ErbB4 in the cerebral cortex and the hippocampus: preferential expression by interneurons tangentially migrating from the ganglionic eminences.
The receptor tyrosine kinases represent an important class of signal transduction molecules that have been shown to play critical… 
Review
2001
Review
2001
The Role of c-erbB-2/HER2/neu in Breast Cancer Progression and Metastasis
Gene amplification and/or overexpression of the c-erbB-2/HER2/neu tyrosine kinase are linked with poor prognosis in breast cancer… 
Highly Cited
1999
Highly Cited
1999
Binding specificities and affinities of egf domains for ErbB receptors
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