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An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
- Xuewu Zhang, Jodi Gureasko, Kui Shen, P. Cole, J. Kuriyan
- Biology, ChemistryCell
- 13 June 2006
The Conformational Plasticity of Protein Kinases
- M. Huse, J. Kuriyan
- Biology, ChemistryCell
- 3 May 2002
The structural basis of the activation of Ras by Sos
- P. Boriack-Sjodin, S. Margarit, D. Bar-Sagi, J. Kuriyan
- Biology, ChemistryNature
- 23 July 1998
TLDR
Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia.
- N. Shah, J. Nicoll, C. Sawyers
- Biology, ChemistryCancer cell
- 1 August 2002
Structural mechanism for STI-571 inhibition of abelson tyrosine kinase.
- T. Schindler, W. Bornmann, P. Pellicena, W. Miller, B. Clarkson, J. Kuriyan
- Biology, ChemistryScience
- 15 September 2000
TLDR
Crystallographic Analysis of the Recognition of a Nuclear Localization Signal by the Nuclear Import Factor Karyopherin α
- E. Conti, Marc Uy, L. Leighton, G. Blobel, J. Kuriyan
- Chemistry, BiologyCell
- 24 July 1998
Crystal Structure of a Tyrosine Phosphorylated STAT-1 Dimer Bound to DNA
- Xiaomin Chen, U. Vinkemeier, Yanxiang Zhao, D. Jeruzalmi, J. Darnell, J. Kuriyan
- Chemistry, BiologyCell
- 29 May 1998
Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA
- T. S. Krishna, X. Kong, S. Gary, P. Burgers, J. Kuriyan
- BiologyCell
- 30 December 1994
Crystal structure of the Src family tyrosine kinase Hck
- F. Sicheri, I. Moarefi, J. Kuriyan
- Chemistry, BiologyNature
- 13 February 1997
TLDR
Structural Basis for the Autoinhibition of c-Abl Tyrosine Kinase
- B. Nagar, O. Hantschel, J. Kuriyan
- Biology, ChemistryCell
- 21 March 2003
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