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Receptor Tyrosine Kinase Inhibitors [MoA]

Known as: Receptor Tyrosine Kinase Inhibitors 
National Institutes of Health

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axitinibceritinibcrizotinibcrizotinib 250 MG Oral Capsule

Papers overview

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Highly Cited
2017
Highly Cited
2017
Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors
Resistance mechanisms against antiangiogenic drugs are unclear. Here, we correlated the antitumor and antivascular properties of… 
2017
2017
Real-time analysis of the binding of fluorescent VEGF165a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexes
Review
2016
Review
2016
Resistance to receptor tyrosine kinase inhibitors in solid tumors: can we improve the cancer fighting strategy by blocking autophagy?
A growing field of evidence suggests the involvement of oncogenic receptor tyrosine kinases (RTKs) in the transformation of… 
Highly Cited
2014
Highly Cited
2014
Expression patterns of RelA and c-mip are associated with different glomerular diseases following anti-VEGF therapy.
Renal toxicity constitutes a dose-limiting side effect of anticancer therapies targeting vascular endothelial growth factor (VEGF… 
2013
2013
Assessing a novel depot delivery strategy for noninvasive administration of VEGF/PDGF RTK inhibitors for ocular neovascular disease.
PURPOSE Two noninvasive delivery strategies for VEGF/PDGF receptor tyrosine kinase inhibitors (RTKI) were explored that exploited… 
2012
2012
A Pooled Analysis of Sequential Therapies with Sorafenib and Sunitinib in Metastatic Renal Cell Carcinoma
Objective: To evaluate the optimal sequence for the receptor tyrosine kinase inhibitors (rTKIs) sorafenib and sunitinib in… 
Highly Cited
2011
Highly Cited
2011
Receptor Tyrosine Kinase Inhibitors Block Multiple Steps of Influenza A Virus Replication
ABSTRACT Host signaling pathways play important roles in the replication of influenza virus, but their functional effects remain… 
Highly Cited
2011
Highly Cited
2011
Receptor Tyrosine Kinase Inhibitors That Block Replication of Influenza A and Other Viruses
ABSTRACT We have previously reported that two receptor tyrosine kinase inhibitors (RTKIs), called AG879 and tyrphostin A9 (A9… 
2007
2007
Receptor tyrosine kinase inhibitors AG013764 and AG013711 reduce choroidal neovascularization in rat eye.
Highly Cited
2005
Highly Cited
2005
Inhibition of platelet-derived growth factor signaling attenuates pulmonary fibrosis
Pulmonary fibrosis is the consequence of a variety of diseases with no satisfying treatment option. Therapy-induced fibrosis also… 
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