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Receptor, TIE-2

Known as: Angiopoietin Receptor Tie 2, Tek Receptor, Receptor Tie-2, Angiopoietin 
A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development… 
National Institutes of Health

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18 relations

Narrower (3)

Angiopoietin-1 Receptor, HumanTek protein, mousetie2 protein, zebrafish
Ephrin Type-A Receptor 2, humanIn BloodProcess of secretionReceptor, TIE-1

Broader (1)

Proteins

Papers overview

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2012
2012
The Tie2 Receptor Antagonist Angiopoietin-2 in Systemic Lupus Erythematosus: Its Correlation with Various Disease Activity Parameters
Background: Systemic lupus erythematosus is one of the autoimmune diseases characterized by multisystem involvement associated… 
Review
2010
Review
2010
Angiopoietins: vascular growth factors looking for roles in glomeruli
Purpose of reviewThe present review highlights general advances concerning angiopoietin (Ang) biology and then focuses on… 
2009
2009
Lipid rafts serve as signaling platforms for Tie2 receptor tyrosine kinase in vascular endothelial cells.
2006
2006
Loss of Tie2 receptor compromises embryonic stem cell-derived endothelial but not hematopoietic cell survival.
Tie2 is a receptor-type tyrosine kinase expressed on hematopoietic stem cells and endothelial cells. We used cultured embryonic… 
Highly Cited
2005
Highly Cited
2005
Gene therapy targeting the Tie2 function ameliorates collagen-induced arthritis and protects against bone destruction.
OBJECTIVE In a previous study, we demonstrated that Tie2 regulates angiogenesis in arthritis. The current study was performed to… 
2001
2001
Identifying substrates for endothelium-specific Tie-2 receptor tyrosine kinase from phage-displayed peptide libraries for high throughput screening.
The peptide substrate specificity of Tie-2 was probed using the phage display method in order to identify efficient substrate for… 
2001
2001
Expression of tyrosine kinase receptors Tie-1 and Tie-2 in giant cell tumor of the tendon sheath: a possible role in synovial proliferation.
We have recently demonstrated that Tie-1 and Tie-2 are expressed in synovial cells from rheumatoid arthritis (RA). To elucidate… 
2000
2000
Genomic structure and alternative splicing of chicken angiopoietin-2.
Angiopoietin-1 (Ang-1) prevents endothelial cell apoptosis and promotes blood vessel stability, while angiopoietin-2 (Ang-2), a… 
2000
2000
The 3T3-L1 Fibroblast to Adipocyte Conversion is Accompanied by Increased Expression of Angiopoietin-1, A Ligand for Tie2
Abstract The tie2 receptor tyrosine kinase plays a key role in angiogenesis, and the remodeling and maturation of blood vessels… 
1997
1997
Tie2 receptor expression and phosphorylation in cultured cells and mouse tissues.
Accumulating experimental evidence indicates that endothelial cell growth and blood vessel morphogenesis are processes that are… 
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