Ephrin Type-A Receptor 2, human

Known as: EC 2.7.1.112, Tyrosine-Protein Kinase Receptor ECK, Epithelial Cell Receptor Protein Tyrosine Kinase 
Ephrin type-A receptor 2 (976 aa, ~108 kDa) is encoded by the human EPHA2 gene. This protein plays a role in ephrin-A binding, cell-cell signaling… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1990-2017
010203019902017

Papers overview

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Highly Cited
2010
Highly Cited
2010
To identify therapeutic targets and prognostic markers for basal breast cancers, breast cancer cell lines were subjected to mass… (More)
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Highly Cited
2008
Highly Cited
2008
EPHA2 receptor tyrosine kinase is overexpressed in several human cancer types and promotes malignancy. However, the mechanisms by… (More)
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Highly Cited
2005
Highly Cited
2005
The EphA2 receptor tyrosine kinase is frequently overexpressed in many cancers, including 40% of breast cancers. Here, we show… (More)
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Highly Cited
2005
Highly Cited
2005
Receptor tyrosine kinases of the Eph family are upregulated in several different types of cancer. One family member in particular… (More)
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Highly Cited
2004
Highly Cited
2004
The EphA2 receptor tyrosine kinase is overexpressed in a variety of human cancers. We sought to characterize the role of EphA2 in… (More)
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Highly Cited
2002
Highly Cited
2002
Eph receptor tyrosine kinases represent promising disease targets because they are differentially expressed in pathologic versus… (More)
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Highly Cited
2002
Highly Cited
2002
EphA2 is a transmembrane receptor tyrosine kinase that is up-regulated on many aggressive carcinoma cells. Despite its… (More)
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Highly Cited
1999
Highly Cited
1999
EphA2 is a member of the Eph family of receptor tyrosine kinases, which are increasingly understood to play critical roles in… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Molecules that are highly expressed by human prostate cancers may serve as therapeutically relevant targets or tumor… (More)
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Highly Cited
1990
Highly Cited
1990
A human epithelial (HeLa) cDNA library was screened with degenerate oligonucleotides designed to hybridize to highly conserved… (More)
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