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Receptor, Notch3

Known as: Notch 3 Receptor, Notch 3 Protein, Notch-3 Receptor 
A notch receptor characterized by a large extracellular domain containing 34 EPIDERMAL GROWTH FACTOR-like repeats. It functions to regulate CELL… 
National Institutes of Health

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NOTCH3 protein, human

Papers overview

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2019
2019
A Study of Congenital Protein C Deficiency With Infancy Onset of CADASIL in a Chinese Baby
Objective: The main objectives of this article were to study a severe congenital protein C deficiency (PCD) in a patient with… 
2019
2019
A new NOTCH3 damaging variant in a thrombocytopenia family of Miao ethnic group
Pediatric inherited thrombocytopenia, also known as a deficiency of platelets in children, is caused by genetic factors and it is… 
Review
2018
Review
2018
The Notch3 Receptor and Its Intracellular Signaling-Dependent Oncogenic Mechanisms.
During evolution, gene duplication of the Notch receptor suggests a progressive functional diversification. The Notch3 receptor… 
2017
2017
[NOTCH3 gene mutations in two Chinese families featuring cerebral autosomal dominant arteriopathy with subcortical infarct and leucoencephalopathy].
OBJECTIVE To analyze potential mutations of the NOTCH3 gene in two Chinese families featuring cerebral autosomal dominant… 
2016
2016
[Extracellular Y-box binding protein-1 promotes proliferation and metastasis of HepG2 cells through Notch3 receptor].
OBJECTIVE To clarify whether HepG2 cells actively secrete Y-box binding protein-1 (YB-1) under stress conditions, and to… 
2014
2014
Protein disulfide bond mapping using online LC – Electrochemistry – MS applied to the characterization of notch 3 protein fragments
The identification of large numbers of proteins is, without doubt, powerful and useful, yet not sufficient in providing a full… 
2014
2014
Abstract 910: NOTCH3 expression is predictive of efficacy in pancreas tumor models treated with OMP-59R5, a monoclonal antibody targeting the NOTCH2 and NOTCH3 receptors
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA The Notch signaling pathway regulates key functions during… 
2011
2011
Extracellular YB-1 Blockade in Experimental Nephritis Upregulates Notch-3 Receptor Expression and Signaling
Background: Notch receptors are involved in kidney development and pathogenesis of inflammatory glomerular diseases. Given the… 
2008
2008
No vessel wall abnormalities in a human foetus with a NOTCH3 mutation
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is hereditary and caused by… 
Review
2008
Review
2008
A Gene for a New Monogenic Neurovascular Migraine Syndrome: A Next Step in Unravelling Molecular Pathways for Migraine?
Migraine is a multifactorial disorder in which both multiple genetic (estimated at up to 61%) and non-genetic factors are… 
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