NOTCH3 protein, human

Known as: Notch homolog 3 (Drosophila) protein, human, Neurogenic Locus Notch Homolog Protein 3, NOTCH3 
Neurogenic locus notch homolog protein 3 (2321 aa, ~244 kDa) is encoded by the human NOTCH3 gene. This protein plays a role in both cell fate… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common… (More)
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Highly Cited
2009
Highly Cited
2009
MicroRNAs contribute to cancer development by acting as oncogenes or tumor suppressor genes. However, only a few microRNA target… (More)
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Highly Cited
2007
Highly Cited
2007
Notch receptors are key regulators of development by controlling cell-fate determination in many multicellular organisms. Genes… (More)
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Highly Cited
2006
Highly Cited
2006
Gene amplification is one of the common mechanisms that activate oncogenes. In this study, we used single nucleotide polymorphism… (More)
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Highly Cited
2005
Highly Cited
2005
Notch3 is a member of an evolutionarily conserved family of cell surface receptors important in cell-fate determination in both… (More)
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Highly Cited
2004
Highly Cited
2004
Formation of a fully functional artery proceeds through a multistep process. Here we show that Notch3 is required to generate… (More)
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Highly Cited
2001
Highly Cited
2001
Notch1 has been shown to induce glia in the peripheral nervous system. However, it has not been known whether Notch can direct… (More)
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Highly Cited
2000
Highly Cited
2000
Mutations in Notch3 cause CADASIL (cerebral autosomal dominant adult onset arteriopathy), which leads to stroke and dementia in… (More)
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Highly Cited
2000
Highly Cited
2000
The multiplicity of Notch receptors raises the question of the contribution of specific isoforms to T-cell development. Notch3 is… (More)
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Highly Cited
1997
Highly Cited
1997
BACKGROUND CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy) is commonly… (More)
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