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NOTCH3 protein, human
Known as:
Notch homolog 3 (Drosophila) protein, human
, Neurogenic Locus Notch Homolog Protein 3
, NOTCH3
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Neurogenic locus notch homolog protein 3 (2321 aa, ~244 kDa) is encoded by the human NOTCH3 gene. This protein plays a role in both cell fate…
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National Institutes of Health
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Related topics
Related topics
15 relations
Ankyrin Repeat
Cell Fate Control
Cellular Membrane
EGF-Like Domain
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Broader (1)
Receptor, Notch3
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
mTORC1 Is Involved in Hypoxia‐Induced Pulmonary Hypertension Through the Activation of Notch3
Wang Wang
,
Jie Liu
,
+6 authors
Jun Wang
Journal of Cellular Physiology
2014
Corpus ID: 40341653
Hypoxia‐induced pulmonary hypertension (HPH) is a clinical syndrome associated with high morbidity and mortality. However, the…
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2012
2012
Overexpression of Angiopoietin-1 Increases CD133+/c-kit+ Cells and Reduces Myocardial Apoptosis in db/db Mouse Infarcted Hearts
H. Zeng
,
Lanfang Li
,
Jian‐Xiong Chen
PLoS ONE
2012
Corpus ID: 17861772
Hematopoietic progenitor CD133+/c-kit+ cells have been shown to be involved in myocardial healing following myocardial infarction…
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2011
2011
CADASIL with cord involvement associated with a novel and atypical NOTCH3 mutation
P. Bentley
,
Tao Wang
,
+4 authors
Pankaj Sharma
Journal of Neurology Neurosurgery & Psychiatry
2011
Corpus ID: 27428823
Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL) is a hereditary…
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Highly Cited
2010
Highly Cited
2010
Notch1 as a potential therapeutic target in cutaneous T-cell lymphoma.
M. Kamstrup
,
L. Gjerdrum
,
+5 authors
R. Gniadecki
Blood
2010
Corpus ID: 1175984
Deregulation of Notch signaling has been linked to the development of T-cell leukemias and several solid malignancies. Yet, it is…
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2009
2009
Hes1 Potentiates T Cell Lymphomagenesis by Up-Regulating a Subset of Notch Target Genes
D. Dudley
,
Hong-cheng Wang
,
Xiao-Hong Sun
PLoS ONE
2009
Corpus ID: 13199100
Background Hairy/Enhancer of Split (Hes) proteins are targets of the Notch signaling pathway and make up a class of basic helix…
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2009
2009
Notch3 and pTalpha/pre-TCR sustain the in vivo function of naturally occurring regulatory T cells.
A. Campese
,
P. Grazioli
,
+8 authors
I. Screpanti
International Immunology
2009
Corpus ID: 205142019
Dysregulated generation and/or function of naturally occurring 'CD4(+)CD25(+) regulatory T cells' (T(reg)s) play key role in the…
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Highly Cited
2006
Highly Cited
2006
Effects of Delta1 and Jagged1 on Early Human Hematopoiesis: Correlation with Expression of Notch Signaling‐Related Genes in CD34+ Cells
Hélia Neves
,
F. Weerkamp
,
+8 authors
L. Parreira
Stem Cells
2006
Corpus ID: 23446197
It has been shown that Notch signaling mediated by ligands of both Jagged and Delta families expands the hematopoietic stem cell…
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Highly Cited
2003
Highly Cited
2003
Active Form of Notch Members Can Enforce T Lymphopoiesis on Lymphoid Progenitors in the Monolayer Culture Specific for B Cell Development1
K. Hozumi
,
N. Abe
,
S. Chiba
,
H. Hirai
,
S. Habu
Journal of Immunology
2003
Corpus ID: 20350134
The in vitro induction of T lymphopoiesis needs the precise stereoscopic structure of thymus tissues as seen in fetal thymus…
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Review
2000
Review
2000
Hereditary Vascular Dementia Linked to Notch 3 Mutations: CADASIL in British Families
N. Thomas
,
C. Morris
,
+11 authors
R. Kalaria
Annals of the New York Academy of Sciences
2000
Corpus ID: 40709607
Abstract: The most common form of familial vascular dementia is considered to be CADASIL or cerebral autosomal dominant…
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Review
2000
Review
2000
CADASIL: Hereditary Arteriopathy Leading to Multiple Brain Infarcts and Dementia
M. Viitanen
,
H. Kalimo
Annals of the New York Academy of Sciences
2000
Corpus ID: 5953504
Abstract: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) often begins with…
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