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Receptor, EphA4
Known as:
Cek 8 Kinase
, Receptor Tyrosine Kinase Eph A4
, Sek 1 Receptor Tyrosine Kinase
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An eph family receptor found in variety of tissues including BRAIN. During embryogenesis, EphA4 receptor exhibits a diverse spatial and temporal…
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National Institutes of Health
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Related topics
Related topics
8 relations
In Blood
Process of secretion
agonists
antagonists & inhibitors
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Development and Structural Analysis of a Nanomolar Cyclic Peptide Antagonist for the EphA4 Receptor
Ilaria Lamberto
,
B. C. Lechtenberg
,
+4 authors
E. Pasquale
ACS Chemical Biology
2014
Corpus ID: 39876800
The EphA4 receptor is highly expressed in the nervous system, and recent findings suggest that its signaling activity hinders…
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2012
2012
Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor.
Ilaria Lamberto
,
Haina Qin
,
+5 authors
E. Pasquale
Biochemical Journal
2012
Corpus ID: 34304802
The EphA4 receptor tyrosine kinase interacts with ephrin ligands to regulate many processes, ranging from axon guidance and nerve…
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2012
2012
Expression and Activation of EphA4 in the Human Brain After Traumatic Injury
Tony Frugier
,
A. Conquest
,
C. Mclean
,
P. Currie
,
D. Moses
,
Y. Goldshmit
Journal of Neuropathology and Experimental…
2012
Corpus ID: 15752173
Abstract Glial scars that consist predominantly of reactive astrocytes create a major barrier to neuronal regeneration after…
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Highly Cited
2010
Highly Cited
2010
GDNF Acts as a Chemoattractant to Support ephrinA-Induced Repulsion of Limb Motor Axons
I. Dudanova
,
Graziana Gatto
,
R. Klein
Current Biology
2010
Corpus ID: 10033573
Highly Cited
2008
Highly Cited
2008
The Rab5 guanylate exchange factor Rin1 regulates endocytosis of the EphA4 receptor in mature excitatory neurons
K. Deininger
,
M. Eder
,
+5 authors
R. Klein
Proceedings of the National Academy of Sciences…
2008
Corpus ID: 2998592
Ephrin signaling through Eph receptor tyrosine kinases regulates important morphogenetic events during development and synaptic…
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Highly Cited
2008
Highly Cited
2008
Overexpression of the receptor tyrosine kinase EphA4 in human gastric cancers.
M. Oki
,
Hiroyuki Yamamoto
,
H. Taniguchi
,
Y. Adachi
,
K. Imai
,
Y. Shinomura
World Journal of Gastroenterology
2008
Corpus ID: 12129541
AIM To clarify the expression and role of Ephrin receptor A4 (EphA4) in gastric cancer in relation to clinicopathological…
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Highly Cited
2008
Highly Cited
2008
Crystal Structure and NMR Binding Reveal That Two Small Molecule Antagonists Target the High Affinity Ephrin-binding Channel of the EphA4 Receptor*
Haina Qin
,
Jiahai Shi
,
R. Noberini
,
E. Pasquale
,
Jianxing Song
Journal of Biological Chemistry
2008
Corpus ID: 29658011
The Eph receptor tyrosine kinases regulate a variety of physiological and pathological processes not only during development but…
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Highly Cited
2007
Highly Cited
2007
Localization of EphA4 in axon terminals and dendritic spines of adult rat hippocampus
M. Tremblay
,
M. Riad
,
+4 authors
G. Doucet
The Journal of comparative neurology
2007
Corpus ID: 894613
Eph receptors and their ephrin ligands assume various roles during central nervous system development. Several of these proteins…
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Review
2003
Review
2003
Physiological, anatomical and genetic identification of CPG neurons in the developing mammalian spinal cord
O. Kiehn
,
S. Butt
Progress in neurobiology
2003
Corpus ID: 22793900
Highly Cited
1998
Highly Cited
1998
Expression and tyrosine phosphorylation of Eph receptors suggest multiple mechanisms in patterning of the visual system.
R. Connor
,
P. Menzel
,
E. Pasquale
Developmental Biology
1998
Corpus ID: 11789599
The EphA3 receptor tyrosine kinase has been implicated in guiding the axons of retinal ganglion cells as they extend in the optic…
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