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Receptor, Endothelin B

Known as: Receptors, Endothelin B, Receptor, Endothelin B [Chemical/Ingredient], Endothelin B Receptors 
Endothelin B receptor (442 aa, ~50 kDa) is encoded by the human EDNRB gene. This protein is involved in vasoconstriction and vasodilation.
National Institutes of Health

Related topics

Related topics

18 relations
EDNRB geneG Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingIn Blood
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EDNRB protein, humanReceptor, Endothelin B, Type 2

Papers overview

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Highly Cited
2008
Highly Cited
2008
Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy
In spite of their having sufficient immunogenicity, tumor vaccines remain largely ineffective. The mechanisms underlying this… Expand
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Highly Cited
2008
Highly Cited
2008
Protective Role of Reactive Astrocytes in Brain Ischemia
Reactive astrocytes are thought to protect the penumbra during brain ischemia, but direct evidence has been lacking due to the… Expand
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Highly Cited
2006
Highly Cited
2006
Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention.
Collecting duct (CD)-derived endothelin-1 (ET-1) inhibits renal Na reabsorption and its deficiency increases blood pressure (BP… Expand
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Highly Cited
2002
Highly Cited
2002
Selective Upregulation of Endothelin B Receptor Gene Expression in Severe Pulmonary Hypertension
Background—The pulmonary circulation is an important site for the production and clearance of endothelin (ET)-1, a potent… Expand
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Highly Cited
2001
Highly Cited
2001
Expression and Localization of Endothelin Receptors: Implications for the Involvement of Peripheral Glia in Nociception
The endothelins (ETs) are peptides that have a diverse array of functions mediated by two receptor subtypes, the endothelin A… Expand
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Highly Cited
2001
Highly Cited
2001
Long Terminal Repeats Are Used as Alternative Promoters for the Endothelin B Receptor and Apolipoprotein C-I Genes in Humans*
To examine the potential regulatory involvement of retroelements in the human genome, we screened the transcribed sequences of… Expand
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Highly Cited
1999
Highly Cited
1999
Inhibition of in vitro enteric neuronal development by endothelin-3: mediation by endothelin B receptors.
The terminal colon is aganglionic in mice lacking endothelin-3 or its receptor, endothelin B. To analyze the effects of… Expand
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Highly Cited
1998
Highly Cited
1998
Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene.
Recent gene targeting studies have revealed unexpected roles for endothelins in the development of neural crest-derived tissues… Expand
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Highly Cited
1998
Highly Cited
1998
SOX10 mutation disrupts neural crest development in Dom Hirschsprung mouse model
Hirschsprung disease (HSCR, MIM ♯142623) is a multigenic neuocristopathy (neural crest disorder) characterized by absence of… Expand
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Highly Cited
1996
Highly Cited
1996
Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer.
The potent vasoconstrictor endothelin-1 (ET-1) is at its highest concentration in the normal human ejaculate and is associated… Expand
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