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Receptor, Endothelin B

Known as: Receptors, Endothelin B, Receptor, Endothelin B [Chemical/Ingredient], Endothelin B Receptors 
Endothelin B receptor (442 aa, ~50 kDa) is encoded by the human EDNRB gene. This protein is involved in vasoconstriction and vasodilation.
National Institutes of Health

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Related topics

18 relations
EDNRB geneG Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingIn Blood

Narrower (2)

EDNRB protein, humanReceptor, Endothelin B, Type 2

Papers overview

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Highly Cited
2007
Highly Cited
2007
Cell-free production of G protein-coupled receptors for functional and structural studies.
Highly Cited
2004
Highly Cited
2004
Endothelin B Receptor Blockade Inhibits Dynamics of Cell Interactions and Communications in Melanoma Cell Progression
Phenotypic and genotypic analyses of cutaneous melanoma have identified the endothelin B receptor (ETBR) as tumor progression… 
Highly Cited
2002
Highly Cited
2002
Exaggerated hypoxic pulmonary hypertension in endothelin B receptor-deficient rats.
Mechanisms by which endothelin (ET)-1 mediates chronic pulmonary hypertension remain incompletely understood. Although activation… 
Highly Cited
2001
Highly Cited
2001
Expression and Localization of Endothelin Receptors: Implications for the Involvement of Peripheral Glia in Nociception
The endothelins (ETs) are peptides that have a diverse array of functions mediated by two receptor subtypes, the endothelin A… 
Highly Cited
2000
Highly Cited
2000
Late endosomal/lysosomal targeting and lack of recycling of the ligand-occupied endothelin B receptor.
A fusion protein consisting of the endothelin B (ET(B)) receptor and the enhanced green fluorescent protein (EGFP) in conjunction… 
Highly Cited
1999
Highly Cited
1999
Expression of endothelin 3 by mesenchymal cells of embryonic mouse caecum
Background Mutations in endothelin 3 (EDN3) and endothelin B receptor (EDNRB) genes cause terminal colonic aganglionosis in mice… 
Highly Cited
1997
Highly Cited
1997
Methylation of the 5' CpG island of the endothelin B receptor gene is common in human prostate cancer.
Production of the potent vasoconstrictor endothelin-1 (ET-1) by human prostate cancer cells accompanies prostate cancer… 
Highly Cited
1997
Highly Cited
1997
Analysis of two pharmacologically predicted endothelin B receptor subtypes by using the endothelin B receptor gene knockout mouse
This study was performed to clarify whether the endothelin (ET) receptor subtypes mediating two pharmacologically heterogeneous… 
Highly Cited
1995
Highly Cited
1995
Growth inhibitory properties of endothelin-1 in human hepatic myofibroblastic Ito cells. An endothelin B receptor-mediated pathway.
Ito cells play a pivotal role in the development of liver fibrosis associated with chronic liver diseases. During this process… 
Highly Cited
1993
Highly Cited
1993
Functionally distinct endothelin B receptors in vascular endothelium and smooth muscle.
IRL 1620 (Suc-[Glu9,Ala11,15]-ET-1 (8-21)) (0.1 nM - 1 microM), a novel ETB-selective endothelin (ET) agonist, produced… 
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