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Receptor, Endothelin B

Known as: Receptors, Endothelin B, Receptor, Endothelin B [Chemical/Ingredient], Endothelin B Receptors 
Endothelin B receptor (442 aa, ~50 kDa) is encoded by the human EDNRB gene. This protein is involved in vasoconstriction and vasodilation.
National Institutes of Health

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Related topics

18 relations
EDNRB geneG Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingIn Blood

Narrower (2)

EDNRB protein, humanReceptor, Endothelin B, Type 2

Papers overview

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2010
2010
Endothelin B receptor stimulation inhibits suicidal erythrocyte death
Endothelins (ETs), potent endothelium‐derived mediators, stimulate formation of nitric oxide, which, in turn, protects against… 
2005
2005
Endothelin B receptor-deficient mice develop endothelial dysfunction independently of salt loading
Background Rodents without a functional endothelin B (ETB) receptor develop salt-sensitive hypertension. The underlying… 
Highly Cited
2002
Highly Cited
2002
The Signal Peptide of the G Protein-coupled Human Endothelin B Receptor Is Necessary for Translocation of the N-terminal Tail across the Endoplasmic Reticulum Membrane*
The initial step of the intracellular transport of G protein-coupled receptors, their insertion into the membrane of the… 
2002
2002
Role of Endothelin B Receptor in the Pathogenesis of Ischemic Acute Renal Failure
This study evaluated the role of endothelin B (ETB) receptor–mediated action in the development and maintenance of ischemic acute… 
Highly Cited
2001
Highly Cited
2001
Role of Endothelin B Receptors in Enhancing Endothelium-Dependent Nitric Oxide–Mediated Vascular Relaxation During High Salt Diet
High salt diet is often associated with increases in blood pressure, and the state of activation of endothelium-dependent… 
2001
2001
Mechanosensitive Transcription Factors Involved in Endothelin B Receptor Expression*
Growing evidence suggests an involvement of the endothelin B receptor (ETB-R) in blood pressure-dependent arterial remodeling. To… 
1999
1999
Endothelin converting enzyme activity in primary rat astrocytes is modulated by endothelin B receptors.
Astrocytes express endothelin-1 (ET-1), ET-3, and their receptors, ET(A) and ET(B). We report here that activated astrocytes in… 
1999
1999
Endothelin B receptors are functionally important in mediating vasoconstriction in the systemic circulation in patients with left ventricular systolic dysfunction.
OBJECTIVES This study was designed to assess the functional importance of endothelin (ET)B receptors in patients with left… 
1997
1997
Characterization of human endothelin B receptor and mutant receptors expressed in insect cells.
Endothelin type-B receptor (ET(B)R) forms a stable complex with its ligand, endothelin-1. To facilitate biochemical and… 
1996
1996
Unique response of human arteries to endothelin B receptor agonist and antagonist.
1. The role of the ET(B) receptor in human arteries has not been well studied because of the lack of specific ET(B) receptor… 
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