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Receptor, Endothelin B

Known as: Receptors, Endothelin B, Receptor, Endothelin B [Chemical/Ingredient], Endothelin B Receptors 
Endothelin B receptor (442 aa, ~50 kDa) is encoded by the human EDNRB gene. This protein is involved in vasoconstriction and vasodilation.
National Institutes of Health

Related topics

Related topics

18 relations
EDNRB geneG Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingIn Blood
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EDNRB protein, humanReceptor, Endothelin B, Type 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Endothelin B Receptor, a New Target in Cancer Immune Therapy
The endothelins and their G protein-coupled receptors A and B have been implicated in numerous diseases and have recently emerged… Expand
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Highly Cited
2008
Highly Cited
2008
Endothelin B receptor mediates the endothelial barrier to T cell homing to tumors and disables immune therapy
In spite of their having sufficient immunogenicity, tumor vaccines remain largely ineffective. The mechanisms underlying this… Expand
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Highly Cited
2006
Highly Cited
2006
Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention.
Collecting duct (CD)-derived endothelin-1 (ET-1) inhibits renal Na reabsorption and its deficiency increases blood pressure (BP… Expand
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Highly Cited
2002
Highly Cited
2002
Selective Upregulation of Endothelin B Receptor Gene Expression in Severe Pulmonary Hypertension
Background—The pulmonary circulation is an important site for the production and clearance of endothelin (ET)-1, a potent… Expand
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Highly Cited
2001
Highly Cited
2001
Long Terminal Repeats Are Used as Alternative Promoters for the Endothelin B Receptor and Apolipoprotein C-I Genes in Humans*
To examine the potential regulatory involvement of retroelements in the human genome, we screened the transcribed sequences of… Expand
Highly Cited
2001
Highly Cited
2001
Expression and Localization of Endothelin Receptors: Implications for the Involvement of Peripheral Glia in Nociception
The endothelins (ETs) are peptides that have a diverse array of functions mediated by two receptor subtypes, the endothelin A… Expand
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Highly Cited
1999
Highly Cited
1999
Inhibition of in vitro enteric neuronal development by endothelin-3: mediation by endothelin B receptors.
The terminal colon is aganglionic in mice lacking endothelin-3 or its receptor, endothelin B. To analyze the effects of… Expand
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Highly Cited
1998
Highly Cited
1998
Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene.
Recent gene targeting studies have revealed unexpected roles for endothelins in the development of neural crest-derived tissues… Expand
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Highly Cited
1998
Highly Cited
1998
SOX10 mutation disrupts neural crest development in Dom Hirschsprung mouse model
Hirschsprung disease (HSCR, MIM ♯142623) is a multigenic neuocristopathy (neural crest disorder) characterized by absence of… Expand
Highly Cited
1996
Highly Cited
1996
Endothelin-1 production and decreased endothelin B receptor expression in advanced prostate cancer.
The potent vasoconstrictor endothelin-1 (ET-1) is at its highest concentration in the normal human ejaculate and is associated… Expand
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