Skip to search formSkip to main contentSkip to account menu

Rats, Inbred WKY

Known as: WISTAR KYOTO, Rats, Wistar Kyoto, Rats, WKY 
An outbred Wistar substrain derived at Kyoto school of medicine and disseminated to the NIH in 1971 and finally to Charles River in 1974. The Wistar… 
National Institutes of Health

Related topics

Related topics

4 relations
Clinical Data Interchange Standards Consortium TerminologyIn BloodMicrobiologicalphysiological aspects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Long-Term Clearance Kinetics of Inhaled Ultrafine Insoluble Iridium Particles from the Rat Lung, Including Transient Translocation into Secondary Organs
Recently it was speculated that ultrafine particles (UFP) may translocate from deposition sites in the lungs to systemic… 
Highly Cited
2002
Highly Cited
2002
Expression and Cellular Localization of Classic NADPH Oxidase Subunits in the Spontaneously Hypertensive Rat Kidney
Phagocytes generate superoxide anion (O2−) by a classic, 5-component NADPH oxidase. O2− contributes to hypertension in… 
Highly Cited
2000
Highly Cited
2000
Vascular NADH/NADPH oxidase is involved in enhanced superoxide production in spontaneously hypertensive rats.
This study was designed to test the hypothesis that stimulation of nicotinamide adenine dinucleotide/nicotinamide adenine… 
Highly Cited
1998
Highly Cited
1998
Normalization of blood pressure and renal vascular resistance in SHR with a membrane-permeable superoxide dismutase mimetic: role of nitric oxide.
Superoxide radical (O2-) is increased in the vessel wall of spontaneously hypertensive rats (SHR) where its blockade potentiates… 
Highly Cited
1995
Highly Cited
1995
Myocardial fibrosis and stiffness with hypertrophy and heart failure in the spontaneously hypertensive rat.
BACKGROUND Fibrosis is commonly found in association with cardiac hypertrophy and failure, but the relation of the connective… 
Highly Cited
1995
Highly Cited
1995
In vivo evidence for microvascular oxidative stress in spontaneously hypertensive rats. Hydroethidine microfluorography.
The factors that predispose to the accelerated organ injury that accompanies the hypertensive syndrome have remained speculative… 
Highly Cited
1994
Highly Cited
1994
Alterations in cardiac gene expression during the transition from stable hypertrophy to heart failure. Marked upregulation of genes encoding extracellular matrix components.
The failing heart is characterized by impaired cardiac muscle function and increased interstitial fibrosis. Our purpose was to… 
Highly Cited
1987
Highly Cited
1987
Effect of dietary alpha-linolenate/linoleate balance on brain lipid compositions and learning ability of rats.
Spontaneously hypertensive rats (SHR) and normotensive control, Wistar/Kyoto (WKY) rats through two generations were fed a… 
Highly Cited
1983
Highly Cited
1983
Role of endothelium in dilator responses of spontaneously hypertensive rat arteries.
The possible role of endothelium in the vascular responses to vasodilator drugs was studied in relation to experimental… 
Highly Cited
1981
Highly Cited
1981
Myosin Isoenzymic Changes in Several Models of Rat Cardiac Hypertrophy
We studied the effect of chronic mechanical overloading on the isoenzymic composition of rat cardiac myosin in several… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)