Raf Kinase Inhibitor

Any substance that inhibits Raf Kinase, an enzyme active in signal transduction in the Ras pathway. Inhibition of Raf kinase may result in reduced… (More)

Topic mentions per year

Topic mentions per year

2001-2016
0246820012016

Papers overview

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2016
2016
BACKGROUND Didymin has been reported to have anti-cancer potential. However, the effect of didymin on liver fibrosis remains… (More)
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2015
2015
Sorafenib is an oral multikinase inhibitor that was originally developed as a Raf kinase inhibitor. We hypothesized that… (More)
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2014
2014
Raf kinase inhibitor protein (RKIP) is a member of the phosphatidylethanolamine-binding-protein (PEBP) family that modulates the… (More)
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2014
2014
Melanoma arising from melanocytes within the choroid is the most frequent primary intraocular neoplasm in adults. It is… (More)
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2011
2011
Hepatocellular carcinoma (HCC) accounts for 80-90% of primary liver tumors and is one of the most common and devastating… (More)
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2011
2011
Raf kinase inhibitor protein (RKIP) is a small, cytosolic protein named for its ability to block Raf-mediated activation of MAPK… (More)
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2011
2011
Raf kinase inhibitory protein (RKIP, also PEBP1) is involved in regulation of multiple cellular signaling processes and… (More)
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2011
2011
Raf kinase inhibitor protein (RKIP) interacts with a number of different proteins and regulates multiple signaling pathways. Here… (More)
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2011
2011
Fibroblast-like synoviocytes (FLS) play an important role in the pathogenesis of rheumatoid arthritis. Raf kinase inhibitor… (More)
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2006
2006
Merkel cell carcinoma (MCC) is a highly metastatic skin tumor. To assess the relevance of the Ras/Raf/MEK/MAP kinase pathway, we… (More)
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