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Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2.

• Anthony Régina, Michel Demeule, +5 authors J-P Castaigne
• British journal of pharmacology
• 2008

BACKGROUND AND PURPOSE Paclitaxel is highly efficacious in the treatment of breast, head and neck, non-small cell lung cancers and ovarian carcinoma. For malignant gliomas, paclitaxel is prevented… (More)

Effect of schisandrin B on hepatic glutathione antioxidant system in mice: protection against carbon tetrachloride toxicity.

• S P S Ip, Maurice Kwong-Lai Poon, +4 authors Kinarm Ko
• Planta medica
• 1995

Pretreating female Balb/c mice with schisandrin B (Sch B) at increasing daily doses (1-4 mmol/kg) for 3 days caused dose-dependent increases in hepatic glutathione S-transferase (GST) and glutathione… (More)

Apoptotic activity of isomalabaricane triterpenes on human promyelocytic leukemia HL60 cells.

• Wing Keung Liu, J C K Ho, C. Che
• Cancer letters
• 2005

Four isomalabaricane triterpenes were isolated from marine sponge Geodia japonica [W.H. Zhang, C.T. Che, Isomalabaricane-type nortriterpenoids and other constituents of the marine sponge Geodia… (More)

Anti-proliferative effect of ginseng saponins on human prostate cancer cell line.

• Wing Keung Liu, S. X. Xu, C. Che
• Life sciences
• 2000

Ginseng is a medicinal herb widely used in Asian countries, and many of its pharmacological actions are attributed to the ginsenosides. In a study of the anti-proliferative activity of ginsenosides… (More)

Folkloric medicinal plants: Tinospora sagittata var. cravaniana and Mahonia bealei.

• T. F. Zhao, Xiaoping Wang, Agnes M Rimando, C. Che
• Planta medica
• 1991

Isomalabaricane-type nortriterpenoids and other constituents of the marine sponge Geodia japonica.

• W. H. Zhang, C. Che
• Journal of natural products
• 2001

Twelve compounds were isolated from the sponge Geodia japonica collected from the South China Sea, including two new isomalabaricane-type nortriterpenoids, geoditins A (1) and B (2), and a new sterol… (More)

Aspergillines A-E, highly oxygenated hexacyclic indole-tetrahydrofuran-tetramic acid derivatives from Aspergillus versicolor.

• Min Zhou, Ming-Ming Miao, +8 authors Xue-Mei Gao
• Organic letters
• 2014

Aspergillines A-E (1-5) are highly oxygenated cyclopiazonic acid (CPA)-derived alkaloids bearing a rigid and sterically congested hexacyclic indole-tetrahydrofuran-tetramate scaffold, isolated from… (More)

Constituents of Croton crassifolius roots.

• L Boonyarathanakornkit, C. Che, H H Fong, N. R. Farnsworth
• Planta medica
• 1988

Peony glycosides produce antidepressant-like action in mice exposed to chronic unpredictable mild stress: effects on hypothalamic-pituitary-adrenal function and brain-derived neurotrophic factor.

• Qing-Qiu Mao, Siu-po Ip, Kam Ming Ko, Sam-Hip Tsai, C. Che
• Progress in neuro-psychopharmacology & biological…
• 2009

The root part of Paeonia lactiflora Pall. (Ranunculaceae), commonly known as peony, is a commonly used Chinese herb for the treatment of depression-like disorders. Previous studies in our laboratory… (More)

New lupane glycosides from Pulsatilla chinensis.

• Wencai Ye, Qingwen Zhang, Wendy Wl Hsiao, Shouxun Zhao, C. Che
• Planta medica
• 2002

Two new lupane glycosides along with five known triterpenoids were isolated from the roots of Pulsatilla chinensis (Ranunculaceae). The structures of the new glycosides were determined to be… (More)

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