Radioimmunotherapy

Known as: Immunotherapy, Cancer, Radioisotope, radioimmunotherapeutics, Immunoradiotherapy 
Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted… (More)
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
PURPOSE Radioimmunotherapy (RIT) with yttrium-90 ((90)Y)-labeled anti-CD20 antibody ((90)Y ibritumomab tiuxetan; Zevalin, IDEC… (More)
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Highly Cited
2003
Highly Cited
2003
UNLABELLED Ibritumomab tiuxetan is an anti-CD20 murine IgG1 kappa monoclonal antibody (ibritumomab) conjugated to the linker… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE Radioimmunotherapy combines biologic and radiolytic mechanisms to target and destroy tumor cells, thus offering a needed… (More)
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Highly Cited
2002
Highly Cited
2002
PURPOSE Rituximab is commonly used as a single agent or in combination therapy for non-Hodgkin's lymphoma (NHL). Ibritumomab… (More)
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Highly Cited
2002
Highly Cited
2002
Mildly thrombocytopenic patients with relapsed or refractory low-grade non-Hodgkin lymphoma (NHL) have an increased risk of… (More)
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Highly Cited
2002
Highly Cited
2002
Relapsed mantle cell lymphoma is a radiation-sensitive malignancy that is unlikely to be cured by treatment with conventional… (More)
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Highly Cited
2000
Highly Cited
2000
CD20-targeted radioimmunotherapy is a promising new treatment for B-cell non-Hodgkin lymphoma (NHL). We now provide updated and… (More)
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Highly Cited
1999
Highly Cited
1999
PURPOSE Yttrium-90 ibritumomab tiuxetan (IDEC-Y2B8) is a murine immunoglobulin G1 kappa monoclonal antibody that covalently binds… (More)
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Highly Cited
1993
Highly Cited
1993
  • G. Sgouros
  • Journal of nuclear medicine : official…
  • 1993
In most implementations of radioimmunotherapy, the red marrow is the dose-limiting organ. Estimates of the radioactivity… (More)
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Highly Cited
1993
Highly Cited
1993
BACKGROUND Many patients with non-Hodgkin's lymphomas are not cured by current therapies, and new approaches to treatment are… (More)
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