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RUNX3 wt Allele

Known as: AML2, PEBP2aC, FLJ34510 
Human RUNX3 wild-type allele is located in the vicinity of 1p36 and is approximately 66 kb in length. This allele, which encodes runt-related… 
National Institutes of Health

Related topics

Related topics

7 relations
1p36Cell Cycle ControlHomo sapiensTranscription, Genetic

Broader (1)

RUNX3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
The Thymidine Dideoxynucleoside Analogue, Alovudine, Inhibits the Mitochondrial DNA Polyermase, POLG, Impairs Oxidative Phosphorylation and Promotes Monocytic Differentiation in AML
Mitochondria contain circular DNA that encodes for 13 proteins that comprise subunits of the respiratory chain and are necessary… 
2016
2016
Targeting cell-bound MUC1 on myelomonocytic leukemias and leukemic stem cells: Therapeutic implications.
e14003Background: Monocytic neoplasms,include chronic myelomonocytic leukemia (CMML), acute myelomonocytic and monocytic leukemia… 
2011
2011
NPMc+ AML cell line shows differential protein expression and lower sensitivity to DNA-damaging and p53-inducing anticancer compounds
Nucleophosmin (NPM), an important regulator in p53 signaling pathway, is one of the most frequently mutated genes in acute… 
2009
2009
Assessment of ATRX expression in patients with myelodysplastic syndromes treated with decitabine.
2007
2007
[Cytology and immunophenotype feautures of 80 acute myeloid leukemia].
Acute myeloid leukemia (AML)'s diagnosis is clinical and biological. We report here 80 AML with cytology and immunophenotype… 
2005
2005
Identification of Marker Genes That Discriminate between Different Myeloproliferative Disorders and Normal Individuals Including RUNX3 (AML2).
Myeloproliferative disorders (MPD) are clonal stem cell diseases, which are defined by excessive production of cells in one or… 
Highly Cited
2000
Highly Cited
2000
Transcriptional regulation of the transforming growth factor-beta -inducible mouse germ line Ig alpha constant region gene by functional cooperation of Smad, CREB, and AML family members.
Smads regulate transcription of defined genes in response to transforming growth factor-beta (TGF-beta) receptor activation. This… 
Highly Cited
1998
Highly Cited
1998
CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter.
TGF-beta1 directs class switching to IgA by splenic B cells and by the surface IgM+ B cell line, I.29mu, by inducing germline (GL… 
Review
1996
Review
1996
Cytogenetic survey of 53 Moroccan patients with acute myeloblastic leukemia.
1995
1995
Mapping of the mouse homolog of the human runt domain gene, AML2, to the distal region of mouse chromosome 4.
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