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RUNX3 gene

Known as: PEBP2A3, AML2 GENE, RUNX3 
This gene is involved in transcriptional regulation.
National Institutes of Health

Related topics

Related topics

7 relations
Cell Cycle ControlCore Binding Factor Alpha 3 SubunitHomo sapiensTranscription, Genetic

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RUNX3 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
MiR-19 regulates the proliferation and invasion of glioma by RUNX3 via β-catenin/Tcf-4 signaling
Accumulating data demonstrates that the network dysregulation of microRNA-medicated target genes is involved in glioma. We have… 
2016
2016
Adverse prognostic impact of the CpG island methylator phenotype in metastatic colorectal cancer
Background:The association between the CpG island methylator phenotype (CIMP) and clinical outcomes in metastatic colorectal… 
Highly Cited
2014
Highly Cited
2014
RUNX3 regulates vimentin expression via miR-30a during epithelial–mesenchymal transition in gastric cancer cells
Runt‐related transcription factor 3 (RUNX3) is a putative tumour suppressor via regulating the expression of a series of target… 
2012
2012
Identification of RUNX3 as a component of the MST/Hpo signaling pathway
Recent genetic screens of fly mutants and molecular analysis have revealed that the Hippo (Hpo) pathway controls both cell… 
Highly Cited
2011
Highly Cited
2011
Restored expression of the tumor suppressor gene RUNX3 reduces cancer stem cells in hepatocellular carcinoma by suppressing Jagged1-Notch signaling.
Runt-related transcription factor 3 (RUNX3) is a candidate tumor suppressor gene that is downregulated in various cancers. In the… 
2010
2010
The novel RUNX3/p33 isoform is induced upon monocyte-derived dendritic cell maturation and downregulates IL-8 expression.
Highly Cited
2008
Highly Cited
2008
Transcriptional repression of the RUNX3/AML2 gene by the t(8;21) and inv(16) fusion proteins in acute myeloid leukemia.
RUNX3/AML2 is a Runt domain transcription factor like RUNX1/AML1 and RUNX2/AML3. Regulated by 2 promoters P1 and P2, RUNX3 is… 
Highly Cited
2005
Highly Cited
2005
RUNX3, A Novel Tumor Suppressor, Is Frequently Inactivated in Gastric Cancer by Protein Mislocalization
Loss of RUNX3 expression is suggested to be causally related to gastric cancer as 45% to 60% of gastric cancers do not express… 
Highly Cited
2001
Highly Cited
2001
Identification of an alternatively spliced form of the mouse AML1/RUNX1 gene transcript AML1c and its expression in early hematopoietic development.
Acute myeloid leukemia 1 (AML1: or runt-related transcription factor, RUNX1) encodes the DNA binding subunit of the… 
1995
1995
Mapping of the mouse homolog of the human runt domain gene, AML2, to the distal region of mouse chromosome 4.
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