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RPA1 wt Allele

Known as: RPA70, REPA1, MST075 
Human RPA1 wild-type allele is located in the vicinity of 17p13.3 and is approximately 70 kb in length. This allele, which encodes replication… 
National Institutes of Health

Related topics

Related topics

7 relations
17p13.3DNA RepairDNA ReplicationRecombination, Genetic

Broader (1)

RPA1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2002
Highly Cited
2002
Molecular Anatomy of the Human Excision Nuclease Assembled at Sites of DNA Damage
ABSTRACT Human nucleotide excision repair is initiated by six repair factors (XPA, RPA, XPC-HR23B, TFIIH, XPF-ERCC1, and XPG… 
Highly Cited
2002
Highly Cited
2002
Analysis of the human replication protein A:Rad52 complex: evidence for crosstalk between RPA32, RPA70, Rad52 and DNA.
Highly Cited
2000
Highly Cited
2000
Human replication protein A: Global fold of the N-terminal RPA-70 domain reveals a basic cleft and flexible C-terminal linker†
Human Replication Protein A (hsRPA) is required for multiple cellular processes in DNA metabolism including DNA repair… 
Highly Cited
1999
Highly Cited
1999
The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single‐stranded DNA binding
Replication protein A (RPA), the eukaryote single‐stranded DNA‐binding protein (SSB), is a heterotrimer. The largest subunit… 
Highly Cited
1996
Highly Cited
1996
Functional domains of the 70-kilodalton subunit of human replication protein A.
Human replication protein A (RPA) is a single-stranded DNA-binding protein that is composed of subunits of 70, 32, and 14 kDa… 
Highly Cited
1996
Highly Cited
1996
Functional complementation of xeroderma pigmentosum complementation group E by replication protein A in an in vitro system.
Xeroderma pigmentosum (XP) is caused by a defect in nucleotide excision repair. Patients in the complementation group E (XP-E… 
Highly Cited
1995
Highly Cited
1995
Human Xeroderma Pigmentosum Group A Protein Interacts with Human Replication Protein A and Inhibits DNA Replication (*)
Human replication protein A (RPA; also known as human single-stranded DNA binding protein, or HSSB) is a multisubunit complex… 
Highly Cited
1994
Highly Cited
1994
Phosphorylation of the p34 subunit of human single-stranded-DNA-binding protein in cyclin A-activated G1 extracts is catalyzed by cdk-cyclin A complex and DNA-dependent protein kinase.
The human single-stranded-DNA-binding protein (HSSB, also called RP-A) is a trimeric complex (p70, p34, and p14) required for… 
Highly Cited
1992
Highly Cited
1992
A role for the human single-stranded DNA binding protein HSSB/RPA in an early stage of nucleotide excision repair.
The human single-stranded DNA binding protein (HSSB/RPA) is involved in several processes that maintain the integrity of the… 
Highly Cited
1990
Highly Cited
1990
Studies on the initiation and elongation reactions in the simian virus 40 DNA replication system.
The synthesis of oligoribonucleotides by DNA primase in the presence of duplex DNA containing the simian virus 40 (SV40) origin… 
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