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RPA1 wt Allele
Known as:
RPA70
, REPA1
, MST075
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Human RPA1 wild-type allele is located in the vicinity of 17p13.3 and is approximately 70 kb in length. This allele, which encodes replication…
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National Institutes of Health
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Related topics
Related topics
7 relations
17p13.3
DNA Repair
DNA Replication
Recombination, Genetic
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Broader (1)
RPA1 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Modulation of Replication Protein A Function by Its Hyperphosphorylation-induced Conformational Change Involving DNA Binding Domain B*
Yiyong Liu
,
M. Kvaratskhelia
,
S. Hess
,
Youxing Qu
,
Y. Zou
Journal of Biological Chemistry
2005
Corpus ID: 34490395
Human replication protein A (RPA), composed of RPA70, RPA32, and RPA14 subunits, undergoes hyperphosphorylation in cells in…
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Highly Cited
1998
Highly Cited
1998
Human RPA (hSSB) interacts with EBNA1, the latent origin binding protein of Epstein-Barr virus.
D. Zhang
,
L. Frappier
,
E. Gibbs
,
J. Hurwitz
,
M. O’Donnell
Nucleic Acids Research
1998
Corpus ID: 16155023
RPA is the replicative single-strand DNA (ssDNA) binding protein of eukaryotic chromosomes. This report shows that human RPA…
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Highly Cited
1997
Highly Cited
1997
Replication Protein A
R. Pfuetzner
,
A. Bochkarev
,
L. Frappier
,
A. Edwards
Journal of Biological Chemistry
1997
Corpus ID: 45978737
Replication protein A (RPA) is a heterotrimeric single-stranded DNA-binding protein in eukaryotic cells. The DNA binding activity…
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Highly Cited
1997
Highly Cited
1997
Mapping of Amino Acid Residues in the p34 Subunit of Human Single-stranded DNA-binding Protein Phosphorylated by DNA-dependent Protein Kinase and Cdc2 Kinase in Vitro *
H. Niu
,
H. Erdjument-Bromage
,
Z. Pan
,
Suk-hee Lee
,
P. Tempst
,
J. Hurwitz
Journal of Biological Chemistry
1997
Corpus ID: 2845152
Human single-stranded DNA-binding protein (HSSB, also called RPA), is a heterotrimeric complex that consists of three subunits…
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Highly Cited
1997
Highly Cited
1997
Complex formation between p53 and replication protein A inhibits the sequence-specific DNA binding of p53 and is regulated by single-stranded DNA
S. Miller
,
K. Moses
,
L. Jayaraman
,
C. Prives
Molecular and Cellular Biology
1997
Corpus ID: 44882541
Human replication protein A (RP-A) (also known as human single-stranded DNA binding protein, or HSSB) is a multisubunit complex…
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Highly Cited
1996
Highly Cited
1996
Functional complementation of xeroderma pigmentosum complementation group E by replication protein A in an in vitro system.
A. Kazantsev
,
D. Mu
,
A. Nichols
,
X. Zhao
,
S. Linn
,
A. Sancar
Proceedings of the National Academy of Sciences…
1996
Corpus ID: 24635679
Xeroderma pigmentosum (XP) is caused by a defect in nucleotide excision repair. Patients in the complementation group E (XP-E…
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Highly Cited
1994
Highly Cited
1994
Phosphorylation of the p34 subunit of human single-stranded-DNA-binding protein in cyclin A-activated G1 extracts is catalyzed by cdk-cyclin A complex and DNA-dependent protein kinase.
Z. Pan
,
A. Amin
,
E. Gibbs
,
H. Niu
,
J. Hurwitz
Proceedings of the National Academy of Sciences…
1994
Corpus ID: 37427116
The human single-stranded-DNA-binding protein (HSSB, also called RP-A) is a trimeric complex (p70, p34, and p14) required for…
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Highly Cited
1994
Highly Cited
1994
Reconstitution of functional human single-stranded DNA-binding protein from individual subunits expressed by recombinant baculoviruses.
E. Stigger
,
F. Dean
,
J. Hurwitz
,
S. Lee
Proceedings of the National Academy of Sciences…
1994
Corpus ID: 29299618
Human single-stranded DNA-binding protein (HSSB), also known as replication protein A, is composed of a 70-kDa single-stranded…
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Highly Cited
1992
Highly Cited
1992
Studies on the initiation of simian virus 40 replication in vitro: RNA primer synthesis and its elongation.
Yota Murakami
,
Toshihiko Eki
,
Jerard Hurwitz
Proceedings of the National Academy of Sciences…
1992
Corpus ID: 6322541
DNA primase-dependent synthesis of oligoribonucleotides 10-15 nucleotides long was observed in the presence of ATP, UTP, GTP, and…
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Highly Cited
1991
Highly Cited
1991
Influence of poly(ADP-ribose) polymerase on the enzymatic synthesis of SV40 DNA.
T. Eki
,
J. Hurwitz
Journal of Biological Chemistry
1991
Corpus ID: 21808001
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