RP1 gene

Known as: OXYGEN-REGULATED PHOTORECEPTOR PROTEIN 1, DCDC4A, RP1 
 
National Institutes of Health

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RETINITIS PIGMENTOSA 1

Papers overview

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2015
2015
Characterizing the roGFP2-Orp1 Fluorescent Biosensor for Detecting Oxidative Stress in Mammalian Cells
Parkinson’s disease is a neurodegenerative disease involving the death of neurons in the substantia nigra and loss of the… (More)
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2012
2012
IGFBP-rP1 induces p21 expression through a p53-independent pathway, leading to cellular senescence of MCF-7 breast cancer cells
ObjectivesInsulin-like growth factor-binding protein (IGFBP)-related protein 1 (IGFBP-rP1), a member of the IGFBP super family… (More)
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2010
2010
The role of active site residues in the oxidant specificity of the Orp1 thiol peroxidase.
In this study we investigated the role of active site residues in the peroxidase activity of Orp1 (GPx3) using three different… (More)
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Highly Cited
2009
Highly Cited
2009
Proximity-based Protein Thiol Oxidation by H2O2-scavenging Peroxidases*♦
H(2)O(2) acts as a signaling molecule by oxidizing critical thiol groups on redox-regulated target proteins. To explain the… (More)
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2007
2007
Molecular mechanism of oxidative stress perception by the Orp1 protein.
In this study we investigated the molecular mechanism by which the Orp1 (Gpx3) protein in Saccharomyces cerevisiae senses and… (More)
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2006
2006
Identification of membrane-bound serine proteinase matriptase as processing enzyme of insulin-like growth factor binding protein-related protein-1 (IGFBP-rP1/angiomodulin/mac25).
Insulin-like growth factor (IGF) binding protein-related protein-1 (IGFBP-rP1) modulates cellular adhesion and growth in an IGF… (More)
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Highly Cited
2003
Highly Cited
2003
The two variants of oxysterol binding protein-related protein-1 display different tissue expression patterns, have different intracellular localization, and are functionally distinct.
Oxysterol binding protein (OSBP) homologs comprise a family of 12 proteins in humans (Jaworski et al., 2001; Lehto et al., 2001… (More)
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2001
2001
Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport.
Oxysterol-binding proteins (OSBPs) are a family of eukaryotic intracellular lipid receptors. Mammalian OSBP1 binds oxygenated… (More)
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2001
2001
Downregulation of the potential suppressor gene IGFBP-rP1 in human breast cancer is associated with inactivation of the retinoblastoma protein, cyclin E overexpression and increased proliferation in…
The complex insulin-like growth factor network of ligands, receptors and binding proteins has been shown to be disturbed in… (More)
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1995
1995
Orp1, a member of the Cdc18/Cdc6 family of S-phase regulators, is homologous to a component of the origin recognition complex.
cdc18+ of Schizosaccharomyces pombe is a periodically expressed gene that is required for entry into S phase and for the… (More)
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