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RP 170

Known as: RP-170 
National Institutes of Health

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2 relations

Broader (2)

NitroimidazolesNucleosides

Papers overview

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2002
2002
Modeling of the anticancer action for radical derivatives of nitroazoles: quantitative structure-activity relationship (QSAR) study.
A QSAR analysis of the anti-tumor, anti-metastasis and anti-colony formation (for metastatic colonies) activities of eighteen… 
1995
1995
Hyperthermia enhances the cytotoxicity against hypoxic cells of RP-170, a new 2-nitroimidazole nucleoside hypoxic cell sensitizer.
The effect of the new hypoxic cell sensitizer, 1-[2-hydroxy-1-(hydroxymethyl)-ethoxy]methyl-2-nitroimidazole (RP-170), combined… 
1994
1994
Metabolic studies and neurotoxicity in tumors and brain of mice after hypoxic cell sensitizers.
1993
1993
Radiosensitization by a new potent nucleoside analog: 1-(1',3',4'-trihydroxy-2'-butoxy)methyl-2-nitroimidazole(RP-343).
1992
1992
Radiosensitization efficacy of KU-2285, RP-170 and etanidazole at low radiation doses: assessment by in vitro cytokinesis-block micronucleus assay.
Since the cytokinesis-block micronucleus assay is very sensitive at low radiation doses, we used it to investigate the in vitro… 
1992
1992
Radiosensitization by 2-nitroimidazole nucleoside analog RP-170: radiosensitizing effects under both intravenous and oral administration.
1990
1990
[Radiosensitization by hypoxic cell radiosensitizer--present status of radiosensitizer].
Because of the unsuccessful clinical trials of misonidazole (MISO), many efforts have been made to find a new hypoxic cell… 
1989
1989
Radiosensitization by a new nucleoside analogue: 1-[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl-2-nitroimidazole (RP-170).
Review
1989
Review
1989
[Present status of radiation sensitizers--hypoxic cell radiosensitizer].
There is a world-wide demand for a clinically usable sensitizer for radio resistant hypoxic cells. Since the unsuccessful… 
Review
1988
Review
1988
[Development of new hypoxic cell radiosensitizer in Japan].
Basic studies in hypoxic cell radiosensitizers developed in Japan were reviewed. Because of the unsuccessful clinical trials of… 
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