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ROS1 gene

Known as: MCF3, ROS proto-oncogene 1, receptor tyrosine kinase, V-ROS UR2 Sarcoma Virus Oncogene Homolog 1 (Avian) Gene 
Highly-expressed in a variety of tumor cell lines, human Oncogene ROS is a mutated variant of ROS1 Gene, which belongs to the sevenless subfamily of… 
National Institutes of Health

Related topics

Related topics

11 relations
6q22Homo sapiensLigand BindingNeoplastic Cell Transformation

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ROS1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Efficacy of immune-checkpoint inhibitors (ICI) in non-small cell lung cancer (NSCLC) patients harboring activating molecular alterations.
172Background: Two revolutions recently occur in the treatment of advanced NSCLC: the development of targeted therapies and of… 
Highly Cited
2014
Highly Cited
2014
Ilimaquinone induces death receptor expression and sensitizes human colon cancer cells to TRAIL-induced apoptosis through activation of ROS-ERK/p38 MAPK-CHOP signaling pathways.
2013
2013
Mutationally activated PIK3CA(H1047R) cooperates with BRAF(V600E) to promote lung cancer progression.
Adenocarcinoma of the lung, a leading cause of cancer death, frequently displays mutational activation of the KRAS proto-oncogene… 
2012
2012
Activation of c-Jun NH(2)-terminal kinase is required for porcine reproductive and respiratory syndrome virus-induced apoptosis but not for virus replication.
2008
2008
Microcystin-RR induced apoptosis in tobacco BY-2 suspension cells is mediated by reactive oxygen species and mitochondrial permeability transition pore status.
Highly Cited
2007
Highly Cited
2007
Suppression of reactive oxygen species production enhances neuronal survival in vitro and in vivo in the anoxia‐tolerant turtle Trachemys scripta
Hypoxia‐ischemia with reperfusion is known to cause reactive oxygen species‐related damage in mammalian systems, yet, the anoxia… 
1997
1997
Mutagenicity and cytotoxicity of reactive oxygen and nitrogen species in the MN-11 murine tumor cell line.
1990
1990
Tissue-specific expression of rat c-ros-1 gene and partial structural similarity of its predicted products with sev protein of Drosophila melanogaster
The expression and predicted products of rat c-ros-1 gene, the proto-oncogene of v-ros in UR2 sarcoma virus, were characterized… 
Highly Cited
1987
Highly Cited
1987
Dual control of Agrobacterium tumefaciens Ti plasmid virulence genes
The virulence genes of nopaline (pTiC58) and octopine (pTiA6NC) Ti plasmids are similarly affected by the Agrobacterium… 
Highly Cited
1982
Highly Cited
1982
Avian sarcoma virus UR2 encodes a transforming protein which is associated with a unique protein kinase activity
UR2 is a newly characterized avian sarcoma virus whose genome contains a unique sequence that is not related to the sequences of… 
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