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ROCK2 gene

Known as: RHO-ASSOCIATED COILED-COIL-CONTAINING PROTEIN KINASE 2, ROCK2, Rho associated coiled-coil containing protein kinase 2 
National Institutes of Health

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2 relations
Protein Kinasesrho-Associated Kinase 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
The level of ROCK1 and ROCK2 in patients with pulmonary hypertension in plateau area
Pulmonary hypertension (PH) is defined as the mean pulmonary artery pressure (mPAP) ≥25 mmHg under the sea level in resting state… 
2016
2016
ROCK2 mediates the proliferation of pulmonary arterial endothelial cells induced by hypoxia in the development of pulmonary arterial hypertension.
It has been reported that RhoA activation and Rho-kinase (ROCK) expression are increased in chronic hypoxic lungs, and the long… 
2015
2015
RhoC and ROCKs regulate cancer cell interactions with endothelial cells
2015
2015
Abrogation of airway hyperresponsiveness but not inflammation by rho kinase insufficiency
Major features of allergic asthma include airway hyperresponsiveness (AHR), eosinophilic inflammation, and goblet cell metaplasia… 
2015
2015
The effect of ROCK on TNF-α-induced CXCL8 secretion by intestinal epithelial cell lines is mediated through MKK4 and JNK signaling.
2015
2015
Rock2 stabilizes β-catenin to promote tumor invasion and metastasis in colorectal cancer.
2011
2011
Peptide Substrates for Rho-Associated Kinase 2 (Rho-Kinase 2/ROCK2)
Peptide substrates sensitive for a certain protein kinase could be important for new-drug development and to understand the… 
2011
2011
Vascular hyperpermeability in response to inflammatory mustard oil is mediated by Rho kinase in mice systemically exposed to arsenic.
2009
2009
The hydrophobic motif of ROCK2 requires association with the N-terminal extension for kinase activity.
ROCK (Rho-associated coiled-coil kinase) 2 is a member of the AGC kinase family that plays an essential role downstream of Rho in… 
Highly Cited
2006
Highly Cited
2006
Rho Kinase Polymorphism Influences Blood Pressure and Systemic Vascular Resistance in Human Twins: Role of Heredity
The Rho/Rho kinase (ROCK) pathway is implicated in experimental hypertension. We, therefore, explored the role of ROCK2 genetic… 
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