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ABSTRACT RNA methylation, catalysed by a set of RNA methyltransferases (RNMTs), modulates RNA structures, properties, and… Expand Summary mRNA cap addition occurs early during RNA Pol II-dependent transcription, facilitating pre-mRNA processing and… Expand Diminished ANK3 contributes to cell survival by inhibiting detachment-induced apoptosis. TP53BP1 that interacts with p53 and MFN1… Expand The mRNA cap is a structure added to RNA pol II transcripts in eukaryotes, which recruits factors involved in RNA processing… Expand Summary The creation of translation-competent mRNA is dependent on RNA polymerase II transcripts being modified by addition of… Expand Maturation and translation of mRNA in eukaryotes requires the addition of the 7-methylguanosine cap. In vertebrates, the cap… Expand Eukaryotic gene expression is dependent on the modification of the first transcribed nucleotide of pre-mRNA by the addition of… Expand Gene expression in eukaryotes is dependent on the mRNA methyl cap which mediates mRNA processing and translation initiation… Expand Summary The 7-methylguanosine cap added to the 5′ end of mRNA is required for efficient gene expression in eukaryotes. In mammals… Expand Cap-dependent mRNA translation requires the methylation of the mRNA guanosine cap by RNA guanine-7-methyltransferase (RNMT). mRNA… Expand