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Alkaloid biosynthesis: metabolism and trafficking.
The application of genomics to the alkaloid field has accelerated the discovery of cDNAs encoding previously elusive biosynthetic enzymes, and technologies, such as large-scale gene expression analyses and metabolic engineering approaches with transgenic plants, have provided new insights into the regulatory architecture of alkaloids metabolism. Expand
Plant aromatic L-amino acid decarboxylases: evolution, biochemistry, regulation, and metabolic engineering applications.
A comprehensive survey of the extensive literature relevant to the evolution, physiology, biochemistry, regulation, and genetic engineering applications of plant aromatic L-amino acid decarboxylases… Expand
ALKALOID BIOSYNTHESIS IN PLANTS: Biochemistry, Cell Biology, Molecular Regulation, and Metabolic Engineering Applications.
- P. Facchini
- Biology, Medicine
- Annual review of plant physiology and plant…
- 1 June 2001
The early events of signal perception, the pathways of signal transduction, and the function of gene promoters have been studied in relation to the regulation of alkaloid metabolism. Expand
Got milk? The secret life of laticifers.
The anatomy, development and physiology of laticifers are discussed with a focus on evolutionary and ecological perspectives. Expand
Hydroxycinnamic acid amide metabolism: physiology and biochemistry
Hydroxycinnamic acid amides (HCAAs) are a widely distributed group of plant secondary metabolites purported to function in several growth and developmental processes including floral induction,… Expand
Quality assessment of ginseng by (1)H NMR metabolite fingerprinting and profiling analysis.
- Eun-Jeong Lee, R. Shaykhutdinov, +5 authors Tae-Jin Yang
- Chemistry, Medicine
- Journal of agricultural and food chemistry
- 5 August 2009
Combined metabolite fingerprinting and profiling suggested that several compounds including glucose, fumarate, and various amino acids could serve as biomarkers for quality assurance in ginseng. Expand
Benzylisoquinoline alkaloid metabolism: a century of discovery and a brave new world.
The growing repository of BIA biosynthetic genes is providing the parts required to apply emerging synthetic biology platforms to the development of production systems in microbes as an alternative to plants as a commecial source of valuable BIAs. Expand
Transcriptome analysis based on next-generation sequencing of non-model plants producing specialized metabolites of biotechnological interest.
A data-mining framework is established, employing next-generation sequencing and computational algorithms, to construct and analyze the transcriptomes of 75 non-model plants that produce compounds of interest for biotechnological applications and the selection of biosynthetic gene candidates associated with six specialized metabolic pathways is described. Expand
Benzylisoquinoline alkaloid biosynthesis in opium poppy
This review highlights recent developments and summarizes the frontiers of knowledge regarding the biochemistry, cellular biology and biotechnology of benzylisoquinoline alkaloid biosynthesis in opium poppy. Expand
Gene family for an elicitor-induced sesquiterpene cyclase in tobacco.
- P. Facchini, J. Chappell
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 15 November 1992
DNA blot-hybridization analysis of genomic DNA revealed a copy number of approximately 12-15 for EAS-like genes in the tetraploid tobacco genome and the conservation of a putative allelic prenyl diphosphate binding motif is discussed. Expand