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RNF4 gene

Known as: RNF4, RING FINGER PROTEIN 4, SLX5 
National Institutes of Health

Related topics

Related topics

2 relations
RNF17 geneRNF4 protein, human

Papers overview

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Highly Cited
2017
Highly Cited
2017
Respiratory syncytial virus induces NRF2 degradation through a promyelocytic leukemia protein ‐ ring finger protein 4 dependent pathway
2014
2014
An Arginine-rich Motif of Ring Finger Protein 4 (RNF4) Oversees the Recruitment and Degradation of the Phosphorylated and SUMOylated Krüppel-associated Box Domain-associated Protein 1 (KAP1)/TRIM28…
Background: The function of KAP1 is regulated by multiple posttranslational modifications during DNA damage response. Results: A… 
Highly Cited
2010
Highly Cited
2010
The SUMO protease SENP6 is essential for inner kinetochore assembly
Kinetochore protein CENP-I is regulated by SUMO protease SENP6 and RNF4, a ubiquitin ligase which targets polysumoylated proteins… 
Highly Cited
2010
Highly Cited
2010
Wss1 Is a SUMO-Dependent Isopeptidase That Interacts Genetically with the Slx5-Slx8 SUMO-Targeted Ubiquitin Ligase
ABSTRACT Protein sumoylation plays an important but poorly understood role in controlling genome integrity. In Saccharomyces… 
Highly Cited
2010
Highly Cited
2010
Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen
DNA methylation is an important epigenetic modification involved in transcriptional regulation, nuclear organization, development… 
Highly Cited
2009
Highly Cited
2009
Role of SUMO in RNF4-mediated Promyelocytic Leukemia Protein (PML) Degradation
Promyelocytic leukemia protein (PML) is a tumor suppressor acting as the organizer of subnuclear structures called PML nuclear… 
Review
2008
Review
2008
A SIM-ultaneous role for SUMO and ubiquitin.
Highly Cited
2008
Highly Cited
2008
Arsenic trioxide stimulates SUMO‐2/3 modification leading to RNF4‐dependent proteolytic targeting of PML
Highly Cited
2007
Highly Cited
2007
SUMO‐targeted ubiquitin ligases in genome stability
We identify the SUMO‐Targeted Ubiquitin Ligase (STUbL) family of proteins and propose that STUbLs selectively ubiquitinate… 
Highly Cited
2007
Highly Cited
2007
Fission Yeast Rnf4 Homologs Are Required for DNA Repair*
We describe two RING finger proteins in the fission yeast Schizosaccharomyces pombe, Rfp1 and Rfp2. We show that these proteins… 
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