RNF139 wt Allele

Known as: Ring Finger Protein 139 wt Allele, TRC8, RCA1 
Human RNF139 wild-type allele is located within 8q24 and is approximately 14 kb in length. This allele, which encodes RING finger protein 139, is… (More)
National Institutes of Health

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Topic mentions per year

1983-2015
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Papers overview

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2012
2012
The endoplasmic reticulum (ER)-resident enzyme 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase catalyzes the rate-limiting… (More)
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2011
2011
Accumulation of sterols in membranes of the endoplasmic reticulum (ER) leads to the accelerated ubiquitination and proteasomal… (More)
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2010
2010
TRC8/RNF139 encodes an endoplasmic reticulum-resident E3 ubiquitin ligase that inhibits growth in a RING- and ubiquitylation… (More)
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2009
2009
RNF139/TRC8 is a potential tumor suppressor gene with similarity to PTCH, a tumor suppressor implicated in basal cell carcinomas… (More)
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2007
2007
TRC8/RNF139 and von Hippel–Lindau (VHL) both encode E3 ubiquitin (Ub) ligases mutated in clear-cell renal carcinomas (ccRCC). VHL… (More)
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2007
2007
Studying the molecular basis of familial renal cell carcinoma (RCC) has allowed identification of novel RCC genes involved in the… (More)
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2002
2002
VHL is part of an SCF related E3-ubiquitin ligase complex with ‘gatekeeper’ function in renal carcinoma. However, no mutations… (More)
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2001
2001
OBJECTIVE To investigate fluorophore linked carbohydrate electrophoresis (FCE) as a method of analyzing serum immunoglobulin G… (More)
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Highly Cited
1999
Highly Cited
1999
A RING finger-containing protein (AO7) that binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent… (More)
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Highly Cited
1998
Highly Cited
1998
The 3;8 chromosomal translocation, t(3;8)(p14.2;q24.1), was described in a family with classical features of hereditary renal… (More)
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