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RNF139 wt Allele

Known as: Ring Finger Protein 139 wt Allele, TRC8, RCA1 
Human RNF139 wild-type allele is located within 8q24 and is approximately 14 kb in length. This allele, which encodes RING finger protein 139, is… Expand
National Institutes of Health

Related topics

Related topics

8 relations
8q24Inhibition of Cell ProliferationRenal Cell CarcinomaTRC8 protein, human
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Broader (2)

RCA1 geneRNF139 gene

Papers overview

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2014
2014
Outcome of triple negative breast cancer: comparison of sporadic and BRCA1-associated cancers
The majority of breast cancers developing in BRCA1 mutation carriers are triple negative breast cancers (TNBC), an aggressive… Expand
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2013
2013
TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 for ubiquitination and degradation
The TRC8 gene, which was previously shown to be disrupted by a 3;8 chromosomal translocation in hereditary kidney cancer, encodes… Expand
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2012
2012
Identification and Functional Characterization of Rca1, a Transcription Factor Involved in both Antifungal Susceptibility and Host Response in Candida albicans
ABSTRACT The identification of novel transcription factors associated with antifungal response may allow the discovery of fungus… Expand
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2009
2009
The tumor suppressor gene TRC8/RNF139 is disrupted by a constitutional balanced translocation t(8;22)(q24.13;q11.21) in a young girl with dysgerminoma
BackgroundRNF139/TRC8 is a potential tumor suppressor gene with similarity to PTCH, a tumor suppressor implicated in basal cell… Expand
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2007
2007
A constitutional balanced t(3;8)(p14;q24.1) translocation results in disruption of the TRC8 gene and predisposition to clear cell renal cell carcinoma.
Studying the molecular basis of familial renal cell carcinoma (RCC) has allowed identification of novel RCC genes involved in the… Expand
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2006
2006
Molecular dissection of the APC/C inhibitor Rca1 shows a novel F-box-dependent function.
Rca1 (regulator of Cyclin A)/Emi (early mitotic inhibitor) proteins are essential inhibitors of the anaphase-promoting complex… Expand
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2003
2003
Performance of the Rossby Centre regional atmospheric model in Southern Sweden: comparison of simulated and observed precipitation
Summary Two climate model simulations made with the Rossby Centre regional Atmospheric model version 1 (RCA1) are evaluated for… Expand
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Highly Cited
2002
Highly Cited
2002
Rca1 inhibits APC-Cdh1(Fzr) and is required to prevent cyclin degradation in G2.
We demonstrate that Rca1 is an essential inhibitor of the anaphase-promoting complex/cyclosome (APC) in Drosophila. APC activity… Expand
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1996
1996
Three genes for mitochondrial proteins suppress null-mutations in both Afg3 and Rca1 when over-expressed
Abstract The AFG3 gene of Saccharomyces cerevisiae encodes a mitochondrial inner membrane protein with ATP-dependent protease… Expand
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1993
1993
The pde2 gene of Saccharomyces cerevisiae is allelic to rca1 and encodes a phosphodiesterase which protects the cell from extracellular cAMP.
The high affinity cAMP phosphodiesterase, encoded by PDE2, is an important component of the cAMP-dependent protein kinase… Expand
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