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RK 28

Known as: RK-28 
National Institutes of Health

Papers overview

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1995
1995
The conditioning effect of rk-28 in a combined treatment with irradiation against v-79 cells.
The conditioning effect of RK-28, one of the nitroimidazole nucleoside analogues, in a combined treatment with irradiation… 
1994
1994
Metabolic studies and neurotoxicity in tumors and brain of mice after hypoxic cell sensitizers.
1994
1994
Preparation and evaluation of suppositories for RK-28 (a new radiosensitizer) using rabbits.
The pharmacokinetics of RK-28 [1-(4-hydroxy-2-butenoxy)methyl-2-nitroimidazole], a new hypoxic cell radiosensitizer, was studied… 
1994
1994
Pharmacokinetics of RK-28 (a new radiosensitizer) and pharmaceutical design of a suppository form using rats.
The pharmacokinetics of RK-28, a new hypoxic cell radiosensitizer, was studied in rats following its intravenous, intraportal… 
1992
1992
Pharmacokinetics of intratumoral RK-28, a new hypoxic radiosensitizer.
1991
1991
Evaluation of a new 2-nitroimidazole nucleoside analogue, RK-28 as a radiosensitizer for clinical use.
The experimental data previously reported on RK-28, a hypoxic cell sensitizer which is now being tested in a phase I clinical… 
1991
1991
P38 19 TP – FUNDAMENTAL AND PHASE I CLINICAL STUDY OF NEW HYPOXIC RADIOSENSITIZER RK-28
1990
1990
[Radiosensitization by hypoxic cell radiosensitizer--present status of radiosensitizer].
Because of the unsuccessful clinical trials of misonidazole (MISO), many efforts have been made to find a new hypoxic cell… 
Review
1989
Review
1989
[Present status of radiation sensitizers--hypoxic cell radiosensitizer].
There is a world-wide demand for a clinically usable sensitizer for radio resistant hypoxic cells. Since the unsuccessful… 
Highly Cited
1987
Highly Cited
1987
Evaluation of various types of new hypoxic cell sensitizers using the EMT6 single cell-spheroid-solid tumour system.
Eleven new hypoxic cell sensitizers representative of those developed in Japan between 1980 and 1985 were evaluated in vitro and… 
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