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RC 121

Known as: RC-121 
National Institutes of Health

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3 relations

Broader (2)

OctreotideSandostatin
analogs & derivatives

Papers overview

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2009
2009
Effect of somatostatin analogs on gastric acid secretion in dogs and rats.
The effects of several superactive analogs of somatostatin on gastric acid response to various exogenous and endogenous… 
2005
2005
Targeted therapy with a cytotoxic somatostatin analog, AN‐238, inhibits growth of human experimental endometrial carcinomas expressing multidrug resistance protein MDR‐1
Chemoresistance mediated by membrane transporters such as multidrug resistance (MDR‐1) glycoprotein remains a challenge in the… 
2005
2005
Growth inhibition of experimental non‐Hodgkin's lymphomas with the targeted cytotoxic somatostatin analogue AN‐238
The cytotoxic analogue of somatostatin, AN‐238, consisting of 2‐pyrrolinodoxorubicin (AN‐201), a superactive derivative of… 
2003
2003
Absence of binding of targeted analogs of somatostatin carrying cytotoxic radicals or radionuclides to growth hormone secretagogue receptors on human myocardium.
Highly Cited
2001
Highly Cited
2001
A targeted cytotoxic somatostatin (SST) analogue, AN-238, inhibits the growth of H-69 small-cell lung carcinoma (SCLC) and H-157 non-SCLC in nude mice.
2000
2000
Regression of U-87 MG human glioblastomas in nude mice after treatment with a cytotoxic somatostatin analog AN-238.
Receptors for somatostatin (SST) found on brain tumors could be used for targeting of chemotherapeutic agents. This study was… 
1999
1999
Inhibition of growth of MX‐1, MCF‐7‐MIII and MDA‐MB‐231 human breast cancer xenografts after administration of a targeted cytotoxic analog of somatostatin, AN‐238
Since somatostatin (sst) receptors are expressed in a high percentage of human breast cancers, we studied the effects of a… 
1988
1988
Comparison of Somatostatin and Its Highly Potent Hexa- and Octapeptide Analogs on Exocrine and Endocrine Pancreatic Secretion
Abstract The effects on pancreatic responses of highly potent cyclic hexapeptide (cyclo (N-Me-Ala-Phe-D-Trp-Lys-Thr-Phe)) (Veber… 
1987
1987
Effects of highly potent octapeptide analogs of somatostatin on growth hormone, insulin and glucagon release.
1987
1987
Inhibitory Effects of Somatostatin Analogs on Prolactin Secretion in Rats Pretreated with Estrogen or Haloperidol
Abstract The effect on prolactin (PRL) secretion of acute administration of new octapeptide analogs of somatostatin (SS) with an… 
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