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RAPGEF4 gene

Known as: RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR, EPAC2, cAMP-GEFII 
National Institutes of Health

Related topics

Related topics

1 relation
RAPGEF3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
AMP-activated protein kinase slows D2 dopamine autoreceptor desensitization in substantia nigra neurons
2019
2019
Overexpression of EPAC2 reduces the invasion of glioma cells via MMP-2
Exchange proteins directly activated by cAMP (EPACs) are crucial cyclic adenosine 3′,5′-monophosphate- determined signaling… 
2019
2019
Cell-specific expression of Epac2 in the subventricular and subgranular zones
cAMP signal transduction cascade activation is important in regulating neurogenesis in adult rodents by increasing the… 
2014
2014
Identification and Validation of Modulators of Epac Activity : Structure-function Implications for Epac Activation and Inhibition
The signaling molecule cAMP primarily mediates its effects by activating PKA and/or Epac. Epac has been implicated in many… 
2012
2012
The microtubule associated protein syntabulin is required for glucose‐stimulated and cAMP‐potentiated insulin secretion
2012
2012
A novel dimerization interface of cyclic nucleotide binding domain, which is disrupted in presence of cAMP: implications for CNG channels gating
AbstractCyclic nucleotide binding domain (CNBD) is a ubiquitous domain of effector proteins involved in signalling cascades of… 
Review
2012
Review
2012
cAMP Sensor Epac and Gastrointestinal Function
2011
2011
[Molecular mechanism of insulin secretion facilitated by incretin].
Incretins, such as GIP and GLP-1 enhance insulin secretion from pancreatic beta cells in a glucose dependent manner. Incretins… 
2006
2006
Activators of Epac proteins induce relaxation of isolated rat aorta
2006
2006
Gene expression profile of the recovering human heart.
Heart failure is a disease of increasing prevalence and poor prognosis. Current data indicate that 5-year survival following the… 
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