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RAPGEF4 gene

Known as: RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR, EPAC2, cAMP-GEFII 
National Institutes of Health

Related topics

Related topics

1 relation
RAPGEF3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
FCPR16, a novel phosphodiesterase 4 inhibitor, produces an antidepressant-like effect in mice exposed to chronic unpredictable mild stress
2019
2019
Selective small-molecule EPAC activators
The cellular signalling enzymes, EPAC1 and EPAC2, have emerged as key intracellular sensors of the secondary messenger cyclic 3… 
2014
2014
Selective β2 adrenergic agonist increases Cx43 and miR-451 expression via cAMP-Epac.
It has been demonstrated that connexin 43 (Cx43) and microRNAs have significant roles in glioma. Cyclic adenosine monophosphate… 
2012
2012
The microtubule associated protein syntabulin is required for glucose‐stimulated and cAMP‐potentiated insulin secretion
2010
2010
Possible role of the exchange protein directly activated by cyclic AMP (Epac) in the cyclic AMP-dependent functional differentiation and syncytialization of human placental BeWo cells.
BACKGROUND The mononuclear villous cytotrophoblast (CTB) differentiates and fuses to the multinucleated syncytiotrophoblast (STB… 
2010
2010
cAMP Analogs and Their Metabolites Enhance TREK-1 mRNA and K+ Current Expression in Adrenocortical Cells
bTREK-1 K+ channels set the resting membrane potential of bovine adrenal zona fasciculata (AZF) cells and function pivotally in… 
2010
2010
Corticotropin releasing factor-induced ERK phosphorylation in AtT20 cells occurs via a cAMP-dependent mechanism requiring EPAC2
2009
2009
cAMP–Epac2‐mediated activation of Rap1 in developing male germ cells: RA‐RhoGAP as a possible direct down‐stream effector
Rap1 is a small GTPase that functions as a positional signal and organizer of cell architecture. Recently Rap1 is emerged to play… 
2006
2006
Activators of Epac proteins induce relaxation of isolated rat aorta
Review
2005
Review
2005
Cyclic nucleotide signalling: a molecular approach to drug discovery for Alzheimer's disease.
The EPAC (exchange protein directly activated by cAMP) proteins are GEFs (guanine nucleotide-exchange factors) that activate Rap… 
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