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RAPGEF3 gene
Known as:
EXCHANGE PROTEIN ACTIVATED BY cAMP
, EPAC1
, Rap guanine nucleotide exchange factor 3
Â
(More)
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National Institutes of Health
Topic mentions per year
Topic mentions per year
1989-2018
0
10
20
1989
2018
Related topics
Related topics
1 relation
RAPGEF4 gene
Related mentions per year
Related mentions per year
1989-2018
1980
1990
2000
2010
2020
RAPGEF3 gene
RAPGEF4 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways.
Yasuhito Onodera
,
Jin-Min Nam
,
Mina J. Bissell
The Journal of clinical investigation
2014
There is a considerable resurgence of interest in the role of aerobic glycolysis in cancer; however, increased glycolysis is…Â
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2013
2013
Opposing Roles of pka and epac in the cAMP-Dependent Regulation of Schwann Cell Proliferation and Differentiation
Ketty Bacallao
,
Paula V Monje
PloS one
2013
In Schwann cells (SCs), cyclic adenosine monophosphate (cAMP) not only induces differentiation into a myelinating SC-related…Â
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2012
2012
Isoform-specific antagonists of exchange proteins directly activated by cAMP.
Tamara N Tsalkova
,
Fang C. Mei
,
+6 authors
Xiaodong Cheng
Proceedings of the National Academy of Sciences…
2012
The major physiological effects of cAMP in mammalian cells are transduced by two ubiquitously expressed intracellular cAMP…Â
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2010
2010
Cyclic AMP phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a vascular endothelial cadherin (VE-Cad)-based signaling complex and controls cAMP-mediated vascular permeability.
Sarah N. Rampersad
,
Jeffrey D Ovens
,
+7 authors
D. Maurice
The Journal of biological chemistry
2010
Vascular endothelial cell (VEC) permeability is largely dependent on the integrity of vascular endothelial cadherin (VE-cadherin…Â
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2008
2008
EPAC and PKA allow cAMP dual control over DNA-PK nuclear translocation.
Elaine Huston
,
Martin J. Lynch
,
+6 authors
Miles D Houslay
Proceedings of the National Academy of Sciences…
2008
We identify a compartmentalized signaling system that identifies a functional role for the GTP exchange factor, exchange protein…Â
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2008
2008
Entropy-driven cAMP-dependent allosteric control of inhibitory interactions in exchange proteins directly activated by cAMP.
Rahul K Das
,
Mohammad T. Mazhab-Jafari
,
Somenath Roy Chowdhury
,
Soumita Sildas
,
Rajeevan Selvaratnam
,
Giuseppe Melacini
The Journal of biological chemistry
2008
Exchange proteins directly activated by cAMP (EPACs) are guanine nucleotide-exchange factors for the small GTPases Rap1 and Rap2…Â
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2008
2008
Epac1 is upregulated during neointima formation and promotes vascular smooth muscle cell migration.
Utako Yokoyama
,
Susumu Minamisawa
,
+9 authors
Yoshihiro Ishikawa
American journal of physiology. Heart and…
2008
Vascular remodeling after mechanoinjury largely depends on the migration of smooth muscle cells, an initial key step to wound…Â
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2007
2007
A chemical biology approach identifies a beta-2 adrenergic receptor agonist that causes human tumor regression by blocking the Raf-1/Mek-1/Erk1/2 pathway
Adam Carie
,
Salwa Sebti
Oncogene
2007
A chemical biology approach identifies a beta 2 adrenergic receptor (β2AR) agonist ARA-211 (Pirbuterol), which causes apoptosis…Â
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2006
2006
Microtubule-associated protein 1B-light chain 1 enhances activation of Rap1 by exchange protein activated by cyclic AMP but not intracellular targeting.
Gillian Borland
,
Mona Gupta
,
Maria M. Magiera
,
Catherine J Rundell
,
Suzanne Fuld
,
Stephen J Yarwood
Molecular pharmacology
2006
We have previously demonstrated that EPAC1 interacts with light chain (LC) 2 of microtubule-associated protein (MAP) 1A. In the…Â
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2006
2006
Presynaptic mechanism underlying cAMP-induced synaptic potentiation in medial prefrontal cortex pyramidal neurons.
Chiung-Chun Huang
,
Kuei-Sen Hsu
Molecular pharmacology
2006
cAMP, a classic second messenger, has been proposed recently to participate in regulating prefrontal cortical cognitive functions…Â
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