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RAPGEF3 gene

Known as: EXCHANGE PROTEIN ACTIVATED BY cAMP, EPAC1, Rap guanine nucleotide exchange factor 3 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Exchange protein directly activated by cAMP (EPAC) and cAMP-dependent protein kinase (PKA) are two intracellular receptors that… Expand
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Highly Cited
2006
Highly Cited
2006
Epac-1 and -2 (exchange proteins directly activated by cyclic AMP) are guanine-nucleotide exchange factors for the GTPases Rap1… Expand
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Highly Cited
2005
Highly Cited
2005
Cyclic adenosine 3′, 5′-monophosphate (cAMP) is a ubiquitous mediator of intracellular signalling events. It acts principally… Expand
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Highly Cited
2005
Highly Cited
2005
cAMP is one of the most important second messenger in the heart. The discovery of Epac as a guanine exchange factor (GEF), which… Expand
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Highly Cited
2004
Highly Cited
2004
Epac1 is a guanine nucleotide exchange factor for Rap1 that is activated by direct binding of cAMP. In vitro studies suggest that… Expand
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Review
2004
Review
2004
Recently published studies of islet cell function reveal unexpected features of glucagon-like peptide-1 (GLP-1) receptor-mediated… Expand
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Highly Cited
2004
Highly Cited
2004
The small GTPase Rap is best characterized as a critical regulator of integrin-mediated cell adhesion, although its mechanism of… Expand
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Highly Cited
2003
Highly Cited
2003
Little is known about the relative role of cAMP-dependent protein kinase (cAPK) and guanine exchange factor directly activated by… Expand
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Highly Cited
2003
Highly Cited
2003
Cyclic adenosine monophosphate (cAMP) is a universal second messenger that, in eukaryotes, was believed to act only on cAMP… Expand
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Highly Cited
2003
Highly Cited
2003
Cyclic AMP (cAMP) is produced by activation of Gs protein-coupled receptors and regulates many physiological processes through… Expand
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