Skip to search formSkip to main contentSkip to account menu

RANBP2 protein, human

Known as: RAN binding protein 2, human, Nucleoporin 358 protein, human, RanBP2 
E3 SUMO-protein ligase RanBP2 (3224 aa, ~358 kDa) is encoded by the human RANBP2 gene. This protein is involved in both protein SUMOylation and… 
National Institutes of Health

Related topics

Related topics

8 relations
Enzyme GeneLigase GeneMitotic Spindle Regulation PathwayNuclear Pore Complex

Broader (1)

ran-binding protein 2

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
The RanBP2/RanGAP1*SUMO1/Ubc9 complex is a multisubunit SUMO E3 ligase.
Highly Cited
2012
Highly Cited
2012
The oncogene eIF4E reprograms the nuclear pore complex to promote mRNA export and oncogenic transformation.
Highly Cited
2011
Highly Cited
2011
HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2
Genome-wide siRNA screens have identified host cell factors important for efficient HIV infection, among which are nuclear pore… 
Highly Cited
2009
Highly Cited
2009
RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin.
The ubiquitin-like SUMO system controls cellular key functions, and several lines of evidence point to a critical role of SUMO… 
Highly Cited
2006
Highly Cited
2006
Functional modulation of parkin through physical interaction with SUMO‐1
Parkinson disease (PD) is the second most common neurodegenerative disorder and is characterized by the extensive and progressive… 
Highly Cited
2005
Highly Cited
2005
Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection
The conjugation of small ubiquitin-like modifiers SUMO-1, SUMO-2 and SUMO-3 onto target proteins requires the concerted action of… 
Highly Cited
2004
Highly Cited
2004
The RanGAP1-RanBP2 Complex Is Essential for Microtubule-Kinetochore Interactions In Vivo
Highly Cited
2004
Highly Cited
2004
The RanBP2 SUMO E3 ligase is neither HECT- nor RING-type
Post-translational modification with the ubiquitin-related protein SUMO1 requires the E1 enzyme Aos1–Uba2 and the E2 enzyme Ubc9… 
Highly Cited
1998
Highly Cited
1998
Ubc9p and the conjugation of SUMO-1 to RanGAP1 and RanBP2
Highly Cited
1995
Highly Cited
1995
GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import
Mediated import of proteins into the nucleus involves multiple cytosolic factors, including the small GTPase Ran. Whether Ran… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)