Nuclear Pore Complex

Known as: Nuclear pore apparatus, NPC, nuclear pore complex (NPC) 
Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC). NPC is comprised of approximately 50 unique proteins… (More)
National Institutes of Health

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Review
2011
Review
2011
In eukaryotic cells, the spatial segregation of replication and transcription in the nucleus and translation in the cytoplasm… (More)
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Review
2010
Review
2010
Although the nuclear pore complex (NPC) is best known for its primary function as the key regulator of molecular traffic between… (More)
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Highly Cited
2007
Highly Cited
2007
Nuclear pore complexes (NPCs) are proteinaceous assemblies of approximately 50 MDa that selectively transport cargoes across the… (More)
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Highly Cited
1998
Highly Cited
1998
We have calculated a three-dimensional map of the yeast nuclear pore complex (yNPC) from frozen-hydrated specimens, thereby… (More)
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Highly Cited
1997
Highly Cited
1997
We have found that the mammalian Ran GTPase-activating protein RanGAP1 is highly concentrated at the cytoplasmic periphery of the… (More)
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Highly Cited
1996
Highly Cited
1996
Ran is a nuclear Ras-like GTPase that is required for the bidirectional transport of proteins and ribnucleoproteins across the… (More)
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Highly Cited
1993
Highly Cited
1993
Nuclear pore complexes (NPCs) have been isolated from the yeast Saccharomyces. Negative stain electron microscopy of the isolated… (More)
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Highly Cited
1992
Highly Cited
1992
A three-dimensional analysis of the nuclear pore complex reveals the underlying, highly symmetric framework of this… (More)
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Highly Cited
1990
Highly Cited
1990
Nuclear pore complexes (NPCs) prepared from Xenopus laevis oocyte nuclear envelopes were studied in "intact" form (i.e… (More)
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Highly Cited
1987
Highly Cited
1987
Using monoclonal antibodies we identified a group of eight polypeptides of rat liver nuclear envelopes that have common epitopes… (More)
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