Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

NUP214 protein, human

Known as: CAIN, CAN protein, human, N214 
Nuclear pore complex protein Nup214 (2090 aa, ~214 kDa) is encoded by the human NUP214 gene. This protein plays a role in the activity of the nuclear… Expand
National Institutes of Health

Related topics

Related topics

9 relations
Carrier ProteinsCell Cycle ProgressionNUP214 geneNuclear Envelope
Expand

Broader (1)

Nuclear Pore Complex Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export.
CRM1 is the major nuclear export receptor. During translocation through the nuclear pore, transport complexes transiently… Expand
Is this relevant?
Highly Cited
2009
Highly Cited
2009
The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner
The DEAD-box protein DBP5 is essential for mRNA export in both yeast and humans. It binds RNA and is concentrated and locally… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • table 1
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Nup214 Is Required for CRM1-Dependent Nuclear Protein Export In Vivo
ABSTRACT Nucleoporins mediate transport of macromolecules across the nuclear pore complex, yet the function of many individual… Expand
Is this relevant?
Highly Cited
2006
Highly Cited
2006
FG-Rich Repeats of Nuclear Pore Proteins Form a Three-Dimensional Meshwork with Hydrogel-Like Properties
Nuclear pore complexes permit rapid passage of cargoes bound to nuclear transport receptors, but otherwise suppress… Expand
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Nup358/RanBP2 Attaches to the Nuclear Pore Complex via Association with Nup88 and Nup214/CAN and Plays a Supporting Role in CRM1-Mediated Nuclear Protein Export
ABSTRACT Nuclear pore complexes (NPCs) traverse the nuclear envelope (NE), providing a channel through which nucleocytoplasmic… Expand
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Structural basis for Nup2p function in cargo release and karyopherin recycling in nuclear import.
The yeast nucleoporin Nup2p is associated primarily with the nuclear basket of nuclear pore complexes and is required for… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus.
The transcription factor Smad2 is released from cytoplasmic retention by TGFbeta receptor-mediated phosphorylation, accumulating… Expand
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Nucleoporins Nup98 and Nup214 Participate in Nuclear Export of Human Immunodeficiency Virus Type 1 Rev
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) Rev contains a leucine-rich nuclear export signal that is essential for its… Expand
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88.
The oncogenic nucleoporin CAN/Nup214 is essential in vertebrate cells. Its depletion results in defective nuclear protein import… Expand
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Cell cycle-dependent phosphorylation of nucleoporins and nuclear pore membrane protein Gp210.
During mitosis in higher eukaryotic cells, the nuclear envelope membranes break down into distinct populations of vesicles and… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE