FAQ

NUP214 protein, human

Known as: CAIN, CAN protein, human, N214 
Nuclear pore complex protein Nup214 (2090 aa, ~214 kDa) is encoded by the human NUP214 gene. This protein plays a role in the activity of the nuclear… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2016
012319982016

Related topics

Related topics

9 relations
Carrier ProteinsCell Cycle ProgressionNUP214 geneNuclear Envelope
(More)

Broader (1)

Nuclear Pore Complex Proteins

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
NUP214 protein, human
Carrier Proteins
Nuclear Envelope
nucleocytoplasmic transport
Structural gene
Nuclear Pore Complex

Papers overview

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2016
2016
Identification and characterization of alpha-I-proteinase inhibitor from common carp sarcoplasmic proteins.
Purification of proteinase inhibitor from common carp (Cyprinus carpio) sarcoplasmic proteins resulted in 2.8% yield with… (More)
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2013
2013
Residues Asn214, Gln211, Glu219 and Gln221 contained in the subfamily 3 catalytic signature of the isocitrate lyase from Pseudomonas aeruginosa are involved in its catalytic and thermal properties.
Isocitrate lyase, encoded by the aceA gene, plays an important role in the ability of Pseudomonas aeruginosa to grow on fatty… (More)
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2012
2012
Episomal amplification of NUP214-ABL1 fusion gene in B-cell acute lymphoblastic leukemia.
The NUP214-ABL1 fusion gene is found amplified as multiple (5-50) episomal copies in 6% of T-cell acute lymphoblastic leukemia (T… (More)
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2011
2011
MRD analysis and treatment outcome in three children with SET-NUP214-positive hematological malignancies.
Sir, Chromosome aberrations that generate fusion genes are common in hematological malignancies. The SETNUP214 fusion gene… (More)
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Highly Cited
2009
Highly Cited
2009
The mRNA export protein DBP5 binds RNA and the cytoplasmic nucleoporin NUP214 in a mutually exclusive manner
The DEAD-box protein DBP5 is essential for mRNA export in both yeast and humans. It binds RNA and is concentrated and locally… (More)
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2009
2009
SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines
BACKGROUND SET-NUP214 fusion resulting from a recurrent cryptic deletion, del(9)(q34.11q34.13) has recently been described in T… (More)
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2008
2008
Involvement of regulations of nucleophosmin and nucleoporins in gambogic acid-induced apoptosis in Jurkat cells.
Gambogic acid, the main active compound of gamboge resin of Garcinia hanburryi, has recently exhibited marked antitumour potency… (More)
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Highly Cited
2004
Highly Cited
2004
Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia
In T-cell acute lymphoblastic leukemia (T-ALL), transcription factors are known to be deregulated by chromosomal translocations… (More)
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2001
2001
Plant development: A short route to cell fate
 
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1998
1998
Overexpression of the nucleoporin CAN/NUP214 induces growth arrest, nucleocytoplasmic transport defects, and apoptosis.
The human CAN gene was first identified as a target of t(6;9)(p23;q34), associated with acute myeloid leukemia and… (More)
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