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RALBP1 wt Allele

Known as: RLIP76, RLIP1, RIP 
Human RALBP1 wild-type allele is located in the vicinity of 18p11.3 and is approximately 63 kb in length. This allele, which encodes ralA-binding… 
National Institutes of Health

Related topics

Related topics

5 relations
18p11.3ChemotaxisRac1 Cell Motility Signaling PathwayRas Signaling Pathway

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Knockdown of RLIP76 expression by RNA interference inhibits invasion, induces cell cycle arrest, and increases chemosensitivity to the anticancer drug temozolomide in glioma cells
RLIP76, a GTPase-activating protein, is a central regulator in multiple pathways that respond to redox states and control cell… 
2012
2012
RLIP76 Regulates PI3K/Akt Signaling and Chemo-Radiotherapy Resistance in Pancreatic Cancer
Purpose Pancreatic cancer is an aggressive malignancy with characteristic metastatic course of disease and resistance to… 
Review
2007
Review
2007
Linking stress-signaling, glutathione metabolism, signaling pathways and xenobiotic transporters
Multi-specific drug-transport mechanisms are intricately involved in mediating a pleiotropic drug-resistance in cancer cells by… 
2006
2006
Determinants of differential doxorubicin sensitivity between SCLC and NSCLC
Highly Cited
2005
Highly Cited
2005
RLIP76 transports vinorelbine and mediates drug resistance in non-small cell lung cancer.
Vinorelbine (Navelbine), an amphiphilic semisynthetic Vinca alkaloid, has displayed superior activity and decreased resistance in… 
Highly Cited
2005
Highly Cited
2005
Depletion of RLIP76 sensitizes lung cancer cells to doxorubicin.
Highly Cited
2003
Highly Cited
2003
Cells Preconditioned with Mild, Transient UVA Irradiation Acquire Resistance to Oxidative Stress and UVA-induced Apoptosis
Because 4-hydroxynonenal (4-HNE) has been suggested to be involved in oxidative stress-mediated apoptosis (Cheng, J. Z., Sharma… 
2003
2003
Role of RLIP76 in lung cancer doxorubicin resistance: I. The ATPase activity of RLIP76 correlates with doxorubicin and 4-hydroxynonenal resistance in lung cancer cells.
RLIP76 functions as an ATP-dependent transporter of amphiphilic chemotherapeutic drugs such as doxorubicin (DOX, adriamycin), as… 
Highly Cited
2003
Highly Cited
2003
Role of RLIP76 in lung cancer doxorubicin resistance: II. Doxorubicin transport in lung cancer by RLIP76.
ATP-dependent transport of doxorubicin (DOX) by recombinant human RLIP76 has been demonstrated previously in reconstituted… 
Highly Cited
2003
Highly Cited
2003
Role of RLIP76 in lung cancer doxorubicin resistance: III. Anti-RLIP76 antibodies trigger apoptosis in lung cancer cells and synergistically increase doxorubicin cytotoxicity.
RLIP76 (ral-binding protein, RalBP1) is a non-ABC multi-specific transporter of amphiphilic chemotherapeutic drugs such as… 
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