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Common variation on 14q24.1, close to RAD51B, has been associated with breast cancer: rs999737 and rs2588809 with the risk of… Expand PURPOSE
The aim of this study was to estimate the contribution of deleterious mutations in the RAD51B, RAD51C, and RAD51D genes… Expand Age-related macular degeneration (AMD) is a common cause of blindness in older individuals. To accelerate the understanding of… Expand BackgroundMost currently known breast cancer predisposition genes play a role in DNA repair by homologous recombination. Recent… Expand The human Rad51 protein is essential for DNA repair by homologous recombination. In addition to Rad51 protein, five paralogs have… Expand Cells defective in any of the RAD51 paralogs (RAD51B, RAD51C, RAD51D, XRCC2, and XRCC3) are sensitive to DNA cross-linking agents… Expand Five Rad51-like proteins, referred to as Rad51 paralogs, have been described in vertebrates. We show that two of them, Rad51B and… Expand In yeast, the Rad51-related proteins include Rad55 and Rad57, which form a heterodimer that interacts with Rad51. Five human… Expand ABSTRACT The highly conserved Saccharomyces cerevisiae Rad51 protein plays a central role in both mitotic and meiotic homologous… Expand Recently, the high mobility group protein gene HMGIC was identified as the chromosome 12q15 target gene in a variety of benign… Expand