RAB8A gene

Known as: ONCOGENE MEL, RAB8A, MEL 
This gene plays a role in signal transduction and protein trafficking.
National Institutes of Health

Papers overview

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2014
2014
The small GTP-binding protein Rab8 is known to play an essential role in intracellular transport and cilia formation. We have… (More)
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2012
2012
The constant self renewal and differentiation of adult intestinal stem cells maintains a functional intestinal mucosa for a… (More)
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Highly Cited
2011
Highly Cited
2011
Autophagy controls the quality and quantity of the eukaryotic cytoplasm while performing two evolutionarily highly conserved… (More)
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Highly Cited
2010
Highly Cited
2010
Skeletal muscle is the primary site of dietary glucose disposal, a function that depends on insulin-mediated exocytosis of GLUT4… (More)
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Highly Cited
2010
Highly Cited
2010
To form epithelial organs cells must polarize and generate de novo an apical domain and lumen. Epithelial polarization is… (More)
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Highly Cited
2008
Highly Cited
2008
Rab8 is a monomeric GTPase that regulates the delivery of newly synthesized proteins to the basolateral surface in polarized… (More)
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Highly Cited
2007
Highly Cited
2007
Cells use multiple pathways to internalize and recycle cell surface components. Although Rab11a and Myosin Vb are involved in the… (More)
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Highly Cited
2002
Highly Cited
2002
We have identified a gene encoding an antigen recognized by cytolytic T lymphocytes on the autologous tumor cells of a melanoma… (More)
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Highly Cited
1999
Highly Cited
1999
Mel 1a melatonin receptors belong to the super-family of guanine nucleotide-binding regulatory protein (G protein)-coupled… (More)
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Highly Cited
1995
Highly Cited
1995
A G protein-coupled receptor for the pineal hormone melatonin was recently cloned from mammals and designated the Mel1a melatonin… (More)
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