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Breast cancer stem cells (BCSCs) constitute a subpopulation of tumor cells that express stem cell-associated markers and have a… Expand Leucine-rich repeat kinase 2 (LRRK2) has been identified as a causative gene for Parkinson's disease (PD). LRRK2 contains a… Expand Rab5, the prototypical Rab GTPase and master regulator of the endocytic pathway, is encoded as three differentially expressed… Expand The Rab11 Family Interacting Proteins (Rab11-FIPs) are hypothesized to regulate sequential steps in the apical recycling and… Expand The leucine-rich repeat kinase 2 (LRRK2) has been identified as the defective gene at the PARK8 locus causing the autosomal… Expand Rab proteins are small GTPases involved in endocytosis and recycling of cell surface molecules. Recently they have been… Expand (S)-3,5-dihydroxyphenylglycine (DHPG), a group I metabotropic glutamate receptor (mGluR1 and 5) agonist reduced NMDA-mediated… Expand The early endosomal autoantigen EEA1 is essential for early endosomal membrane fusion. It binds to endosomes via a C-terminal… Expand To explore the potential role of Rab GTPases in human insulin resistance, we first employed a PCR-cloning approach to identify… Expand Rab proteins are small GTPases involved in the regulation of membrane traffic. Rab5a has been shown to regulate transport in the… Expand