RAB27A gene

Known as: HsT18676, GS2, RAB27A 
This gene plays a role in the formation and release of lymphocytic granules.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Tumor-derived exosomes are emerging mediators of tumorigenesis. We explored the function of melanoma-derived exosomes in the… (More)
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Highly Cited
2012
Highly Cited
2012
During progression from single cancer cells to a tumor mass and metastases, tumor cells send signals that can subvert their… (More)
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Highly Cited
2010
Highly Cited
2010
Exosomes are secreted membrane vesicles that share structural and biochemical characteristics with intraluminal vesicles of… (More)
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Highly Cited
2003
Highly Cited
2003
Vesicular transport is a complex multistep process regulated by distinct Rab GTPases. Here, we show for the first time that an… (More)
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Highly Cited
2002
Highly Cited
2002
Recently, we identified and characterized a novel protein, granuphilin, whose domain structure is similar to that of the Rab3… (More)
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Highly Cited
2002
Highly Cited
2002
The Rab27a GTPase regulates diverse processes involving lysosome-related organelles, including melanosome motility in melanocytes… (More)
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Highly Cited
2001
Highly Cited
2001
Rab27a activity is affected in several mouse models of human disease including Griscelli (ashen mice) and Hermansky-Pudlak… (More)
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Highly Cited
2001
Highly Cited
2001
Rab GTPases are regulators of intracellular membrane traffic. We report a possible function of Rab27a, a protein implicated in… (More)
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Highly Cited
2000
Highly Cited
2000
Griscelli syndrome (GS, MIM 214450), a rare, autosomal recessive disorder, results in pigmentary dilution of the skin and the… (More)
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Highly Cited
2000
Highly Cited
2000
The dilute (d), leaden (ln), and ashen (ash) mutations provide a unique model system for studying vesicle transport in mammals… (More)
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