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RAB27A gene

Known as: HsT18676, GS2, RAB27A 
This gene plays a role in the formation and release of lymphocytic granules.
National Institutes of Health

Related topics

Related topics

6 relations
ExocytosisGRISCELLI SYNDROME, TYPE 2Homo sapiensRAB13 gene

Papers overview

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2016
2016
Rab3A, Rab27A, and Rab35 regulate different events during mouse oocyte meiotic maturation and activation
Rab family members play important roles in membrane trafficking, cell growth, and differentiation. Almost all components of the… 
Review
2013
Review
2013
Evidence for defective Rab GTPase-dependent cargo traffic in immune disorders.
2013
2013
Identification of Novel Rab27a/Melanophilin Blockers by Pharmacophore-Based Virtual Screening
Melanocytes are unique cells that produce specific melanin-containing intracellular organelles called melanosomes. Melanosomes… 
2012
2012
MUNC13-4 Protein Regulates the Oxidative Response and Is Essential for Phagosomal Maturation and Bacterial Killing in Neutrophils*
Background: MUNC13-4 regulates vesicular trafficking, and its deficiency causes immunodeficiency in humans. Results: MUNC13-4… 
2012
2012
Essential Role of RAB27A in Determining Constitutive Human Skin Color
Human skin color is predominantly determined by melanin produced in melanosomes within melanocytes and subsequently distributed… 
2010
2010
Actin assembly controlled by GDP-Rab27a is essential for endocytosis of the insulin secretory membrane.
2009
2009
Redistribution of small GTP-binding protein, Rab27B, in rat parotid acinar cells after stimulation with isoproterenol.
Small GTP-binding protein, Rab27, has been implicated in the regulation of different types of membrane trafficking, including… 
Highly Cited
2008
Highly Cited
2008
Docking is not a Prerequisite but a Temporal Constraint for Fusion of Secretory Granules
We examined secretory granule dynamics using total internal reflection fluorescence microscopy in normal pancreatic β cells and… 
2008
2008
Role of Rab27 in synaptic transmission at the squid giant synapse
Small GTPase Rab is a member of a large family of Ras-related proteins, highly conserved in eukaryotic cells, and thought to… 
2005
2005
Akt Regulates the Subcellular Localization of the Rab27a‐Binding Protein JFC1 by Phosphorylation
Here, we show that the Rab27a‐binding protein JFC1/Slp1 (synaptotagmin‐like protein) is regulated by Akt‐mediated phosphorylation… 
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