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R115777
Known as:
R 115777
, R-115777
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
tipifarnib
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
in vitro autonomous erythropoiesis of polycythemia vera patient cells Farnesyltransferase inhibitor tipifarnib (R115777) preferentially inhibits
Padua Ra
,
C. Chomienne
,
+5 authors
M. Schlageter
2013
Corpus ID: 82543800
2008
2008
The farnesyltransferase inhibitor R115777 (ZARNESTRA®) enhances the pro-apoptotic activity of interferon-α through the inhibition of multiple survival pathways (International Journal of Cancer (2007…
M. Caraglia
,
M. Marra
,
+11 authors
P. Tagliaferri
2008
Corpus ID: 78808399
2007
2007
Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (ZarnestraMT).
F. Alyaqoub
,
L. Tao
,
+4 authors
Michael A. Pereira
Carcinogenesis
2007
Corpus ID: 33110126
Budesonide (an anti-inflammatory glucocorticoid), R115777 (a farnesyl transferase inhibitor, Zarnestra, Tipifarnib) or…
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2007
2007
The Farnesyltransferase Inhibitor R 115777 Upregulates the Expression of Death Receptor 5 and Enhances TRAIL-Induced Apoptosis in Human Lung Cancer Cells
Yuan-Zheng Qiu
,
Xiang-Guo Liu
,
+4 authors
Shi-Yong Sun
2007
Corpus ID: 30364414
Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) preferentially induces apoptosis in transformed or malignant…
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2007
2007
TRAIL-Induced Apoptosis in Human Lung Cancer Cells Expression of Death Receptor 5 and Enhances The Farnesyltransferase Inhibitor R 115777 Upregulates the
Yuan-Zheng Qiu
,
Xiang-Guo Liu
,
+4 authors
Shi-Yong Sun
2007
Corpus ID: 17118640
Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) preferentially induces apoptosis in transformed or malignant…
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2004
2004
Phase I and pharmacokinetic study of the farnesyltransferase inhibitor R115777 in combination with irinotecan in patients with advanced cancer
S. J. Cohen
,
J. Gallo
,
+10 authors
N. Meropol
Cancer Chemotherapy and Pharmacology
2004
Corpus ID: 22403770
PurposeR115777 is a selective, nonpeptidomimetic inhibitor of farnesyltransferase (FTase), an enzyme responsible for the post…
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2002
2002
Current Clinical Trials of R115777 (Zarnestra)
J. Wright
,
K. Zerivitz
,
A. Gravell
2002
Corpus ID: 155451986
R115777 (Zarnestra) is an orally available methylquinolone derivative from Johnson & Johnson Pharmaceutical Research and…
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2001
2001
Therapeutic and chemopreventive effects of R115777, a farnesyl transferase inhibitor (FTI), on methylnitrosourea (MNU)-induced rat mammary cancer
Lubet Ra
,
M. You
,
+4 authors
C. Grubbs
2001
Corpus ID: 80235469
2001
2001
A phase I, clinical and pharmacokinetic trial of Zarnestra (farnesyl transferase inhibitor, R115777) and docetaxel : a promising combination in patients with solid tumors
A. Awada
,
T. Gil
,
+7 authors
M. Piccart-Gebhart
2001
Corpus ID: 104359701
2000
2000
Phase I Trial of Oral R115777 in Patients with Refractory Solid Tumors: Preliminary Results
G. Hudes
,
Jessie Schol
2000
Corpus ID: 79099137