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Quinpirole

Known as: 1H-Pyrazolo(3,4-g)quinoline, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, (4aR-trans)-, Quinpirole [Chemical/Ingredient] 
A dopamine D2/D3 receptor agonist.
National Institutes of Health

Papers overview

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Highly Cited
1999
Highly Cited
1999
We measured endogenous cannabinoid release in dorsal striatum of freely moving rats by microdialysis and gas chromatography/mass… Expand
Highly Cited
1998
Highly Cited
1998
Rats treated chronically with the dopamine agonist quinpirole (0.5 mg/kg, twice weekly x 10) met 5 criteria for performance of… Expand
Highly Cited
1997
Highly Cited
1997
Cannabinoids act at the CB1 receptor to inhibit adenylate cyclase activity via a pertussis toxin-sensitive G-protein. Within the… Expand
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Highly Cited
1997
Highly Cited
1997
Dopamine has been shown to stimulate phosphorylation of DARPP-32, a phosphoprotein highly enriched in medium-sized spiny neurons… Expand
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Highly Cited
1995
Highly Cited
1995
The D2 dopamine (DA) receptor agonist, quinpirole, was characterized in young adult monkeys, young reserpine-treated monkeys and… Expand
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Highly Cited
1995
Highly Cited
1995
Methods for the assessment of akinesia in the unilateral rat Parkinson model have so far been lacking. The experiments reported… Expand
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Highly Cited
1993
Highly Cited
1993
In the mammalian neostriatum, dopamine modulates neuronal responses mediated by activation of excitatory amino acid receptors… Expand
Highly Cited
1990
Highly Cited
1990
The striatum, which is the major component of the basal ganglia in the brain, is regulated in part by dopaminergic input from the… Expand
Highly Cited
1987
Highly Cited
1987
1. Intracellular recordings were made from neurones in the substantia nigra zona compacta in slices of rat mesencephalon in vitro… Expand
Highly Cited
1987
Highly Cited
1987
The behaviour of rats was studied after combined treatment with the selective DA D-2 agonist quinpirole and three selective D-1… Expand