Quinpirole

Known as: 1H-Pyrazolo(3,4-g)quinoline, 4,4a,5,6,7,8,8a,9-octahydro-5-propyl-, (4aR-trans)-, Quinpirole [Chemical/Ingredient] 
A dopamine D2/D3 receptor agonist.
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
Dopamine (DA) input to the prefrontal cortex (PFC), acting on D1 receptors, plays an essential role in mediating working memory… (More)
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Highly Cited
1999
Highly Cited
1999
We measured endogenous cannabinoid release in dorsal striatum of freely moving rats by microdialysis and gas chromatography/mass… (More)
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Highly Cited
1998
Highly Cited
1998
Rats treated chronically with the dopamine agonist quinpirole (0.5 mg/kg, twice weekly x 10) met 5 criteria for performance of… (More)
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Highly Cited
1997
Highly Cited
1997
Cannabinoids act at the CB1 receptor to inhibit adenylate cyclase activity via a pertussis toxin-sensitive G-protein. Within the… (More)
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Highly Cited
1997
Highly Cited
1997
Dopamine has been shown to stimulate phosphorylation of DARPP-32, a phosphoprotein highly enriched in medium-sized spiny neurons… (More)
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Highly Cited
1995
Highly Cited
1995
The D2 dopamine (DA) receptor agonist, quinpirole, was characterized in young adult monkeys, young reserpine-treated monkeys and… (More)
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Highly Cited
1993
Highly Cited
1993
Prepulse inhibition (PPI) of the startle reflex is reduced by systemic administration of dopamine (DA) agonists. Since PPI is… (More)
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1993
1993
It is known that dopamine (DA) receptors can be sensitized by repeated treatments with quinpirole during postnatal development… (More)
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Highly Cited
1990
Highly Cited
1990
The striatum, which is the major component of the basal ganglia in the brain, is regulated in part by dopaminergic input from the… (More)
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Highly Cited
1989
Highly Cited
1989
The effects of the D-2 agonist quinpirole on forward progression, and on vertical and lateral movements, were measured for 2 h in… (More)
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