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Quinine remains an important anti-malarial drug almost 400 years after its effectiveness was first documented. However, its… Expand Summary Background Severe malaria is a major cause of childhood death and often the main reason for paediatric hospital admission… Expand To the Editor: Although artemisinins are potent and rapidly acting antimalarial drugs, their widespread use for treating patients… Expand The global dissemination of drug-resistant Plasmodium falciparum is spurring intense efforts to implement artemisinin (ART)-based… Expand BACKGROUND
In the treatment of severe malaria, intravenous artesunate is more rapidly acting than intravenous quinine in terms of… Expand The emergence and spread of multidrug resistant Plasmodium falciparum has severely limited the therapeutic options for the… Expand Much of natural product chemistry concerns a group of compounds known as secondary metabolites. These low-molecular-weight… Expand What roles do mesolimbic and neostriatal dopamine systems play in reward? Do they mediate the hedonic impact of rewarding stimuli… Expand SummaryMalaria is associated with a reduction in the systemic clearance and apparent volume of distribution of the cinchona… Expand A rapid, semiautomated microdilution method was developed for measuring the activity of potential antimalarial drugs against… Expand