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Quinine

Known as: (R)-(-)-Quinine, Quinine [Chemical/Ingredient], 6'-Methoxycinchonidine 
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (20)

9-O-(phenyloxycarbonyl)quinineDiapulmonLimptarN-benzylquininium

Broader (4)

AlkaloidsAnalgesicsAntimalarialsMuscle Relaxants, Central
Cinchona (plant)Drug toxicityIn BloodMalaria

Papers overview

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Highly Cited
2007
Highly Cited
2007
Contact information for corresponding author :
Users may access full items free of charge; copies of full text items generally can be reproduced, displayed or performed and… 
Highly Cited
2006
Highly Cited
2006
Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin.
The global dissemination of drug-resistant Plasmodium falciparum is spurring intense efforts to implement artemisinin (ART)-based… 
Highly Cited
2005
Highly Cited
2005
The quest for quinine: those who won the battles and those who won the war.
For a long time, the synthesis of quinine constituted an elusive target. In 2004, which marked the 60th anniversary of the… 
Highly Cited
2000
Highly Cited
2000
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum
Throughout the latter half of this century, the development and spread of resistance to most front-line antimalarial compounds… 
Highly Cited
2000
Highly Cited
2000
The tyrosine-86 allele of the pfmdr1 gene of Plasmodium falciparum is associated with increased sensitivity to the anti-malarials mefloquine and artemisinin.
Highly Cited
1999
Highly Cited
1999
Averting a malaria disaster
Highly Cited
1983
Highly Cited
1983
Minimal model for membrane oscillations in the pancreatic beta-cell.
Highly Cited
1980
Highly Cited
1980
Lymphocyte membrane potential assessed with fluorescent probes.
Highly Cited
1978
Highly Cited
1978
The taste reactivity test. II. Mimetic responses to gustatory stimuli in chronic thalamic and chronic decerebrate rats
Highly Cited
1965
Highly Cited
1965
Drug resistance in Plasmodium berghei Vincke and Lips, 1948. I. Chloroquine resistance.
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