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Quinine

Known as: (R)-(-)-Quinine, Quinine [Chemical/Ingredient], 6'-Methoxycinchonidine 
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (20)

9-O-(phenyloxycarbonyl)quinineDiapulmonLimptarN-benzylquininium

Broader (4)

AlkaloidsAnalgesicsAntimalarialsMuscle Relaxants, Central
Cinchona (plant)Drug toxicityIn BloodMalaria

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
The Woodward-Doering/Rabe-Kindler total synthesis of quinine: setting the record straight.
In 1918, Paul Rabe and Karl Kindler reported the three-step conversion of d-quinotoxine into quinine. In 1944 Robert B. Woodward… 
2007
2007
Genetic polymorphisms involved in toxicant-metabolizing enzymes and the risk of chronic benzene poisoning in Chinese occupationally exposed populations
  • Y. ChenG. Li D. Ma
  • Xenobiotica; the fate of foreign compounds in…
  • 2007
  • Corpus ID: 42251538
Benzene is a recognized haematotoxin and leukaemogen, but its mechanism of action and the role of genetic susceptibility are… 
Highly Cited
2004
Highly Cited
2004
Drug resistance in Plasmodium falciparum from the Chittagong Hill Tracts, Bangladesh
Objective  To assess the efficacy of antimalarial treatment and molecular markers of Plasmodium falciparum resistance in the… 
1999
1999
Quinine-Induced Hepatotoxicity
OBJECTIVE: To report a case of quinine-induced hepatotoxicity presenting within 24 hours following the ingestion of the first… 
Highly Cited
1988
Highly Cited
1988
Inhibition of desipramine 2‐hydroxylation by quinidine and quinine
Urinary excretion of desipramine (DMI) and 2‐hydroxydesipramine (2‐OH‐DMI) after single oral doses of 25 mg DMI was investigated… 
Highly Cited
1986
Highly Cited
1986
Sensitivity to quinine and mefloquine of Plasmodium falciparum in Thailand.
Between 1982 and 1984 a regimen consisting of quinine and tetracycline was routinely used in Thailand to treat outpatients with… 
Highly Cited
1986
Highly Cited
1986
On the mechanism by which dicyclohexylcarbodiimide and quinine inhibit K+ transport in rat liver mitochondria.
Passive uptake of potassium acetate into the mitochondrial matrix can be induced by nigericin, a K+/H+ antiporter, or by A23187… 
1982
1982
Alkaloid Production by Leaf Organ, Root Organ and Cell Suspension Cultures of Cinchona ledgeriana
Cinchona ledgeriana 
1982
1982
Calcium channel and calcium pump involved in oscillatory hyperpolarizing responses of L‐strain mouse fibroblasts
1. In fibroblastic L cells, spontaneously repeated hyperpolarizing responses (oscillation of membrane potential) and… 
Highly Cited
1971
Highly Cited
1971
Nuclear magnetic resonance spectroscopy. Carbon-13 spectra of nicotine, quinine, and some Amaryllidaceae alkaloids.
The natural-abundance ^(13)C magnetic resonance spectra of nicotine, quinine, several Amaryllidaceae alkaloids, and selected… 
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