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Quinine

Known as: (R)-(-)-Quinine, Quinine [Chemical/Ingredient], 6'-Methoxycinchonidine 
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona… 
National Institutes of Health

Related topics

Related topics

44 relations

Narrower (20)

9-O-(phenyloxycarbonyl)quinineDiapulmonLimptarN-benzylquininium

Broader (4)

AlkaloidsAnalgesicsAntimalarialsMuscle Relaxants, Central
Cinchona (plant)Drug toxicityIn BloodMalaria

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Quinine, an old anti-malarial drug in a modern world: role in the treatment of malaria
Quinine remains an important anti-malarial drug almost 400 years after its effectiveness was first documented. However, its… 
Highly Cited
2010
Highly Cited
2010
Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial
Highly Cited
2008
Highly Cited
2008
Evidence of artemisinin-resistant malaria in western Cambodia.
To the Editor: Although artemisinins are potent and rapidly acting antimalarial drugs, their widespread use for treating patients… 
Highly Cited
2005
Highly Cited
2005
Artesunate versus quinine for treatment of severe falciparum malaria: a randomised trial
Highly Cited
2005
Highly Cited
2005
pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum
The emergence and spread of multidrug resistant Plasmodium falciparum has severely limited the therapeutic options for the… 
Review
1998
Review
1998
What is the role of dopamine in reward: hedonic impact, reward learning, or incentive salience?
Review
1996
Review
1996
Pharmacokinetics of Quinine, Chloroquine and Amodiaquine
SummaryMalaria is associated with a reduction in the systemic clearance and apparent volume of distribution of the cinchona… 
Highly Cited
1982
Highly Cited
1982
Fluorescence quantum yields of some rhodamine dyes
Highly Cited
1979
Highly Cited
1979
Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique
A rapid, semiautomated microdilution method was developed for measuring the activity of potential antimalarial drugs against… 
Highly Cited
1978
Highly Cited
1978
The taste reactivity test. I. Mimetic responses to gustatory stimuli in neurologically normal rats
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